0001001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 1001002 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 1002003 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 1003004 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS link:presentationLink link:calculationLink link:definitionLink 1004005 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS link:presentationLink link:calculationLink link:definitionLink 1005006 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY link:presentationLink link:calculationLink link:definitionLink 1006007 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 2101101 - Disclosure - Organization link:presentationLink link:calculationLink link:definitionLink 2402401 - Disclosure - Organization - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 2103102 - Disclosure - Basis of Presentation link:presentationLink link:calculationLink link:definitionLink 2204201 - Disclosure - Basis of Presentation (Policies) link:presentationLink link:calculationLink link:definitionLink 2305301 - Disclosure - Basis of Presentation (Tables) link:presentationLink link:calculationLink link:definitionLink 2406402 - Disclosure - Basis of Presentation - Supplementary cash flows information (Details) link:presentationLink link:calculationLink link:definitionLink 2407403 - Disclosure - Basis of Presentation - Reconciliation of Cash, Cash Equivalents and Restricted Cash (Details) link:presentationLink link:calculationLink link:definitionLink 2108103 - Disclosure - Recent Accounting Pronouncements link:presentationLink link:calculationLink link:definitionLink 2109104 - Disclosure - Revenue link:presentationLink link:calculationLink link:definitionLink 2310302 - 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Disclosure - Net Loss Per Common Share (Details) link:presentationLink link:calculationLink link:definitionLink 2136111 - Disclosure - Nexobrid License and Supply Agreements link:presentationLink link:calculationLink link:definitionLink 2437417 - Disclosure - Nexobrid License and Supply Agreements (Details) link:presentationLink link:calculationLink link:definitionLink 2138112 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 2339309 - Disclosure - Commitments and Contingencies (Tables) link:presentationLink link:calculationLink link:definitionLink 2440418 - Disclosure - Commitments and Contingencies - Future Minimum Payments (Details) link:presentationLink link:calculationLink link:definitionLink 2440418 - Disclosure - Commitments and Contingencies - Future Minimum Payments (Details) link:presentationLink link:calculationLink link:definitionLink