Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization Consolidation and Presentation of Financial Statements [Table] Organization Consolidation and Presentation of Financial Statements [Table] Disclosure pertaining to organization, consolidation and presentation of financial statements. Business Acquisition [Axis] Business Acquisition [Axis] Business Acquisition, Acquiree [Domain] Business Acquisition, Acquiree [Domain] CTRM Business Cell Therapy And Regenerative Medicine Business [Member] Represents information pertaining to cell therapy and regenerative medicine business. Organization Organization Consolidation and Presentation of Financial Statements [Line Items] Number of patents and patents applications acquired Number of Patents and Patent Applications Acquired Represents the number of patents and patent applications acquired by the entity. Number of reportable segments Number of Reportable Segments Accumulated deficit Retained Earnings (Accumulated Deficit) Net loss Net Income (Loss) Attributable to Parent Cash Cash Earnings Per Share [Abstract] NET LOSS PER COMMON SHARE Earnings Per Share [Text Block] Numerator: Net Income (Loss) Attributable to Parent [Abstract] Net loss Dividends accumulated on convertible preferred stock Preferred Stock Dividends, Income Statement Impact Net loss attributable to common shareholders Net Income (Loss) Available to Common Stockholders, Basic Denominator: Weighted Average Number of Shares Outstanding, Diluted [Abstract] Weighted-average common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Basic and Diluted Net loss per share attributable to common shareholders (basic and diluted) (in dollars per share) Earnings Per Share, Basic and Diluted Aggregate number of common equivalent shares (related to options, warrants and preferred stock) that have been excluded from computations of diluted net loss per common share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Fair Value Disclosures [Abstract] FAIR VALUE MEASUREMENTS Fair Value Disclosures [Text Block] Document and Entity Information Entity Registrant Name Entity Registrant Name Entity Central Index Key Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Entity Filer Category Entity Filer Category Document Type Document Type Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Amendment Flag Amendment Flag Entity Common Stock, Shares Outstanding (in shares) Entity Common Stock, Shares Outstanding Disclosure of Compensation Related Costs, Share-based Payments [Abstract] STOCK-BASED COMPENSATION Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Balance Sheet Related Disclosures [Abstract] Accounts payable and accrued expenses: Accounts Payable and Accrued Liabilities, Current [Abstract] Bonus related compensation Accrued Bonuses Employee related accruals Employee-related Liabilities, Current Clinical trial related accruals Accrued Liabilities, Current Other Deferred Revenue, Current Total Accounts Payable and Accrued Liabilities, Current BASIS OF PRESENTATION BASIS OF PRESENTATION Basis of Accounting [Text Block] SELECTED BALANCE SHEET COMPONENTS Supplemental Balance Sheet Disclosures [Text Block] Commitments and Contingencies Disclosure [Abstract] COMMITMENTS AND CONTINGENCIES Commitments and Contingencies Disclosure [Text Block] Equity [Abstract] PREFERRED STOCK Preferred Stock [Text Block] Inventory: Inventory, Net [Abstract] Raw materials Inventory, Raw Materials, Gross Work-in-process Inventory, Work in Process, Gross Finished goods Inventory, Finished Goods, Gross Inventory Inventory, Net Accounting Policies [Abstract] RECENT ACCOUNTING PRONOUNCEMENTS Significant Accounting Policies [Text Block] Statement of Cash Flows [Abstract] Operating activities: Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Adjustments to reconcile net loss to net cash used for operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Depreciation and amortization Depreciation, Depletion and Amortization Stock compensation expense Share-based Compensation Change in fair value of warrants Fair Value Adjustment of Warrants Inventory provision Inventory Write-down Foreign currency translation loss Foreign Currency Transaction Gain (Loss), before Tax Changes in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] Inventory Increase (Decrease) in Inventories Accounts receivable Increase (Decrease) in Receivables Other current assets Increase (Decrease) in Other Current Assets Accounts payable Increase (Decrease) in Accounts Payable and Accrued Liabilities Accrued expenses Increase (Decrease) in Employee Related Liabilities Tenant improvement reimbursement Increase (Decrease) In Tenant Improvement Reimbursement Increase (Decrease) In Tenant Improvement Reimbursement Deferred rent expense Increase (Decrease) in Deferred Charges Other assets and liabilities, net Increase (Decrease) in Other Operating Assets and Liabilities, Net Net cash used for operating activities Net Cash Provided by (Used in) Operating Activities Investing activities: Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Expenditures for property, plant and equipment Payments to Acquire Businesses, Net of Cash Acquired Net cash used in investing activities Net Cash Provided by (Used in) Investing Activities Financing activities: Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Net proceeds from issuance of common stock Proceeds from Issuance of Preferred Stock and Preference Stock Deferred financing costs Payments of Debt Issuance Costs Borrowings under revolving credit agreement and term loan Proceeds from Secured Lines of Credit Repayments of short-term debt Repayments of Short-term Debt Payments on long-term debt Repayments of Long-term Debt Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities Net decrease in cash Cash and Cash Equivalents, Period Increase (Decrease) Cash at beginning of period Cash at end of period Supplemental cash flow information (non-cash): Noncash Investing and Financing Items [Abstract] Additions to equipment in process included in accounts payable Preferred Stock, Accretion of Redemption Discount Conversion of preferred stock into common stock Stock Issued Warrants issued in connection with debt arrangement Debt Conversion, Converted Instrument, Amount Supplementary cash flows information: Supplemental Cash Flow Information [Abstract] Interest paid, net of interest capitalized Interest Paid Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Award Type [Axis] Award Type [Axis] Equity Award [Domain] Equity Award [Domain] Service-Based Stock Options Employee Stock Option [Member] Income Statement Location [Axis] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] Cost of goods sold Cost of Sales [Member] Research and development Research and Development Expense [Member] Research and development Selling, General and Administrative Expenses [Member] Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Total non-cash stock-based compensation expense Allocated Share-based Compensation Expense Schedule of future minimum payments related to leases Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block] Schedule of Stock by Class [Table] Schedule of Stock by Class [Table] Class of Stock [Axis] Class of Stock [Axis] Class of Stock [Domain] Class of Stock [Domain] Preferred Class A And Class B Preferred Class A And Class B [Member] Preferred Class A And Class B [Member] Common Class A Common Class A [Member] Convertible Preferred Stock Class of Stock [Line Items] Conversion of stock, converted (in shares) Conversion of Stock, Shares Converted Accumulated undeclared dividends (in shares) Accumulated Undeclared Dividends Shares Represents the accumulated shares but undeclared dividends related to convertible preferred stock. Conversion of stock, issued (in shares) Conversion of Stock, Shares Issued Schedule of net loss attributable to common shareholders and share data used in the basic and diluted earnings per share computations using the two class method Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Stockholders' Equity Note [Abstract] SHAREHOLDERS' EQUITY Stockholders' Equity Note Disclosure [Text Block] Schedule of non-cash stock-based compensation expense Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] Schedule of weighted average assumptions used to estimate fair value of each service-based stock option grant Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Summary of activity for service-based stock options Share-based Compensation, Stock Options, Activity [Table Text Block] Summary of valuation of the Company's investments and financial instruments that are measured at fair value on a recurring basis Fair Value, Liabilities Measured on Recurring Basis [Table Text Block] Summary of change in estimated fair value of warrant liabilities Schedule of Change in Estimated Fair Value of Warrant Liabilities [Table Text Block] Tabular disclosure of change in the estimated fair value of the warrant liabilities. Warrants and Rights Note Disclosure [Abstract] Schedule of warrants outstanding Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] Schedule of assumptions used in calculating estimated fair value of warrants Schedule of Class of Warrant or Right Valuation Assumptions [Table Text Block] Tabular disclosure of the significant assumptions used during the period to estimate the fair value of warrant liabilities, including, but not limited to: (a) expected term of instruments, (b) expected volatility of the entity's shares, (c) closing stock price, (d) risk-free rate, and (e) dividend rate. STOCK PURCHASE WARRANTS Warrants and Rights Note Disclosure [Text Block] The entire disclosure for warrants including description, amounts outstanding, fair value calculation and estimates. Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Employee Stock Employee Stock [Member] Range [Axis] Range [Axis] Range [Domain] Range [Domain] Minimum Minimum [Member] Maximum Maximum [Member] Subsequent Event Type [Axis] Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event Type [Domain] Subsequent Event Subsequent Event [Member] Stock-Based Compensation Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Vesting period Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period Expiration period Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period Grant date fair value (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Weighted average assumptions used to estimate fair value of each service-based stock option grant Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract] Expected dividend rate Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected stock price volatility Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate Risk-free interest rate Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Expected life Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Options Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Outstanding at the beginning of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Exercised (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Expired (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Expirations in Period Forfeited (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Outstanding at the end of the period (in shares) Exercisable at the end of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Weighted Average Exercise Price Share Based Compensation Arrangement by Share Based Payment Award Options Outstanding, Weighted Average Exercise Price [Abstract] Outstanding at the beginning of the period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Granted (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Exercised (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Expired (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Forfeited (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Outstanding at the end of the period (in dollars per share) Exercisable at the end of the period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Weighted Average Remaining Contractual Term Share Based Compensation Arrangement by Share Based Payment Award Options, Weighted Average Remaining Contractual Term [Abstract] Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Exercisable at the end of the period Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Aggregate Intrinsic Value Share Based Compensation Arrangement By Share Based Payment Award Options Aggregate Intrinsic Value [Abstract] Share Based Compensation Arrangement By Share Based Payment Award Options Aggregate Intrinsic Value [Abstract] Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value Exercised Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value Exercisable at end of period Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value Total unrecognized compensation cost Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options Weighted average period over which unrecognized compensation is expected to be recognized Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition Total fair value of options vested Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value Stock issued during period, employee stock purchase plans (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Stock issued during period, employee stock purchase plans Stock Issued During Period, Value, Employee Stock Purchase Plan Schedule of inventory Schedule of Inventory, Current [Table Text Block] Schedule of property and equipment, net Property, Plant and Equipment [Table Text Block] Schedule of accounts payable and accrued expenses Schedule of Accounts Payable and Accrued Liabilities [Table Text Block] Risks and Uncertainties [Abstract] REVENUE Concentration Risk Disclosure [Text Block] Concentration Risk [Table] Concentration Risk [Table] Customer [Axis] Customer [Axis] Customer [Domain] Customer [Domain] Carticel Carticel [Member] Carticel [Member] Carticel And MACI Distributor Carticel And MACI Distributor [Member] Carticel And MACI Distributor [Member] Largest Customer Largest Customer [Member] Largest Customer [Member] Second Largest Customer Second Largest Customer [Member] Second Largest Customer [Member] Valuation Allowances and Reserves Type [Axis] Valuation Allowances and Reserves Type [Axis] Valuation Allowances and Reserves [Domain] Valuation Allowances and Reserves [Domain] Allowance for Receivable from Insurance Provider Allowance for Receivable from Insurance Provider [Member] Valuation Allowances And Reserves Period [Axis] Valuation Allowances And Reserves Period [Axis] Valuation Allowances And Reserves Period [Axis] Valuation Allowances And Reserves Period [Domain] Valuation Allowances And Reserves Period [Domain] [Domain] for Valuation Allowances And Reserves Period [Axis] Valuation Allowances And Reserves Period, Related To 2016 Valuation Allowances And Reserves Period, Related To 2016 [Member] Valuation Allowances And Reserves Period, Related To 2016 [Member] Valuation Allowances And Reserves Period, Related To 2017 Valuation Allowances And Reserves Period, Related To 2017 [Member] Valuation Allowances And Reserves Period, Related To 2017 [Member] Change in Accounting Estimate by Type [Axis] Change in Accounting Estimate by Type [Axis] Change in Accounting Estimate, Type [Domain] Change in Accounting Estimate, Type [Domain] Disputes Disputes [Member] Counterparty Name [Axis] Counterparty Name [Axis] Counterparty Name [Domain] Counterparty Name [Domain] Orsini Orsini Pharmaceutical services, Inc. [Member] Orsini Pharmaceutical services, Inc. [Member] Concentration Risk Type [Axis] Concentration Risk Type [Axis] Concentration Risk Type [Domain] Concentration Risk Type [Domain] Customer concentration Customer Concentration Risk [Member] Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Domain] Concentration Risk Benchmark [Domain] Revenue Sales Revenue, Net [Member] Accounts Receivable Accounts Receivable [Member] CONCENTRATION Concentration Risk [Line Items] Provision for rebates and cash discounts Sales Discounts, Returns and Allowances, Goods Revenue reserves, deductions Valuation Allowances and Reserves, Deductions Revenue reserves, reversal of change in estimate Valuation Allowances and Reserves, Additions for Adjustments Distribution agreement, number of additional terms Distribution Agreement, Number Of Additional Terms Distribution Agreement, Number Of Additional Terms Distribution agreement, additional term Distribution Agreement, Additional Term Distribution Agreement, Additional Term Concentration risk Concentration Risk, Percentage ORGANIZATION Nature of Operations [Text Block] Statement of Financial Position [Abstract] Statement [Table] Statement [Table] Series B-2 Series B Preferred Stock [Member] Statement Statement [Line Items] Allowance for doubtful accounts Allowance for Doubtful Accounts Receivable Current portion of term loan credit agreement, deferred costs Debt Issuance Costs, Current, Net Revolving and term loan credit agreement, deferred costs Debt Issuance Costs, Noncurrent, Net Convertible preferred stock, authorized (in shares) Preferred Stock, Shares Authorized Convertible preferred stock, reserved (in shares) Convertible Preferred Stock, Shares Reserved for Future Issuance Convertible preferred stock, issued (in shares) Preferred Stock, Shares Issued Convertible preferred stock, outstanding (in shares) Preferred Stock, Shares Outstanding Common Stock, authorized (in shares) Common Stock, Shares Authorized Common Stock, issued (in shares) Common Stock, Shares, Issued Common Stock, outstanding (in shares) Common Stock, Shares, Outstanding Innovative Cellular Therapeutics Innovative Cellular Therapeutics [Member] Innovative Cellular Therapeutics [Member] Common Stock Common Stock [Member] Class of Stock [Line Items] License agreement, initial payment License Agreement, Initial Payment License Agreement, Initial Payment License agreement, days within effective date of agreement initial payment due License Agreement, Days Within Effective Date Of Agreement Initial Payment Due License Agreement, Days Within Effective Date Of Agreement Initial Payment Due License agreement, contingent consideration, asset License Agreement, Contingent Consideration, Asset License Agreement, Contingent Consideration, Asset License agreement, contingent consideration, liability License Agreement, Contingent Consideration, Liability License Agreement, Contingent Consideration, Liability Warrants issued (in dollars per share) Class Of Warrant Or Right, Purchase Price Of Warrants Or Rights Class Of Warrant Or Right, Purchase Price Of Warrants Or Rights Exercise price per share (in dollars per share) Class of Warrant or Right, Exercise Price of Warrants or Rights Debt Disclosure [Abstract] Schedule of Long-term Debt Instruments [Table] Schedule of Long-term Debt Instruments [Table] Lender Name [Axis] Lender Name [Axis] Line of Credit Facility, Lender [Domain] Line of Credit Facility, Lender [Domain] Silicon Valley Bank Silicon Valley Bank [Member] Silicon Valley Bank [Member] Debt Instrument [Axis] Debt Instrument [Axis] Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] Debt Financing Agreement Debt Financing Agreement [Member] Debt Financing Agreement [Member] Term Loan Term Loan [Member] Term Loan [Member] Debt Instrument, Redemption, Period [Axis] Debt Instrument, Redemption, Period [Axis] Debt Instrument, Redemption, Period [Domain] Debt Instrument, Redemption, Period [Domain] Debt Instrument, Redemption, Period One Debt Instrument, Redemption, Period One [Member] Debt Instrument, Redemption, Period Two Debt Instrument, Redemption, Period Two [Member] Debt Instrument, Redemption, Period Three Debt Instrument, Redemption, Period Three [Member] Credit Facility [Axis] Credit Facility [Axis] Credit Facility [Domain] Credit Facility [Domain] Revolving Credit Facility Revolving Credit Facility [Member] Long-term Debt, Type [Axis] Long-term Debt, Type [Axis] Long-term Debt, Type [Domain] Long-term Debt, Type [Domain] Line of Credit Line of Credit [Member] Variable Rate [Axis] Variable Rate [Axis] Variable Rate [Domain] Variable Rate [Domain] Prime Rate Prime Rate [Member] Covenant Period [Axis] Covenant Period [Axis] Covenant Period [Axis] Covenant Period [Domain] Covenant Period [Domain] [Domain] for Covenant Period [Axis] December 31, 2017 December 31, 2017 [Member] December 31, 2017 [Member] Debt Instrument [Line Items] Debt Instrument [Line Items] Debt instrument, face amount Debt Instrument, Face Amount Maximum borrowing capacity (up to) Debt Financing Agreement, Maximum Borrowing Capacity Debt Financing Agreement, Maximum Borrowing Capacity Line of credit facility, maximum borrowing capacity Line of Credit Facility, Maximum Borrowing Capacity Basis spread on variable rate Debt Instrument, Basis Spread on Variable Rate Number of installments Debt Instrument, Number of Installments Debt Instrument, Number of Installments Short-term bank loans and notes payable Short-term Bank Loans and Notes Payable Line of credit, current Line of Credit, Current Weighted average interest rate Debt, Weighted Average Interest Rate Minimum revenue covenant Line of Credit Facility, Minimum Revenue Covenant Line of Credit Facility, Minimum Revenue Covenant Remaining borrowing capacity Line of Credit Facility, Remaining Borrowing Capacity Cowen Cowen and Company, LLC [Member] Cowen and Company, LLC [Member] At-the-market sales agreement, maximum aggregate proceeds At-The-Market Sales Agreement, Maximum Aggregate Proceeds At-The-Market Sales Agreement, Maximum Aggregate Proceeds Percentage of gross proceeds payable as commission Percentage of Gross Proceeds Payable as Commission Represents the percentage of gross proceeds payable as commission. At-the-market sales agreement, shares issued (in shares) At-the-Market Sales Agreement, Shares Issued At-the-Market Sales Agreement, Shares Issued At-the-market sales agreement, proceeds from issuance of common stock At-The-Market-Sales Agreement, Proceeds From Issuance Of Common Stock At-The-Market-Sales Agreement, Proceeds From Issuance Of Common Stock Payments of stock issuance costs Payments of Stock Issuance Costs Amount of net capacity remaining on the at-the-market sales agreement Common Stock Remaining Capacity Represents the amount of remaining capacity of common stock. Series B-2 ASSETS Assets [Abstract] Current assets: Assets, Current [Abstract] Accounts receivable (net of allowance for doubtful accounts of $226 and $225, respectively) Accounts Receivable, Net, Current Inventory Other current assets Other Assets, Current Total current assets Assets, Current Property and equipment, net Property, Plant and Equipment, Net Total assets Assets LIABILITIES AND SHAREHOLDERS’ EQUITY Liabilities and Equity [Abstract] Current liabilities: Liabilities, Current [Abstract] Accounts payable Accounts Payable, Current Accrued expenses Current portion of term loan credit agreement (net of deferred costs of $110) Line of Credit and Term Loan Credit Agreement, Current, Net of Deferred Costs Line of Credit and Term Loan Credit Agreement, Current, Net of Deferred Costs Warrant liabilities Derivative Liability, Current Other Other Liabilities, Current Total current liabilities Liabilities, Current Long term deferred rent Long-term Debt, Excluding Current Maturities Revolving and term loan credit agreement (net of deferred costs of $211 and $293, respectively) Deferred Rent Credit, Noncurrent Other long term debt Other Liabilities, Noncurrent Total liabilities Liabilities COMMITMENTS AND CONTINGENCIES (Note 13) Commitments and Contingencies Shareholders’ equity: Stockholders' Equity Attributable to Parent [Abstract] Series B-2 voting convertible preferred stock, no par value: shares authorized and reserved — 39, shares issued and outstanding — 0 and 12, respectively Preferred Stock, Value, Outstanding Common stock, no par value; shares authorized — 75,000; shares issued and outstanding — 34,852 and 31,595, respectively Common Stock, Value, Issued Warrants Warrants and Rights Outstanding Accumulated deficit Total shareholders’ equity Stockholders' Equity Attributable to Parent Total liabilities and shareholders’ equity Liabilities and Equity Recent Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Property, Plant and Equipment, Type [Axis] Property, Plant and Equipment, Type [Axis] Property, Plant and Equipment, Type [Domain] Property, Plant and Equipment, Type [Domain] Machinery and equipment Machinery and Equipment [Member] Furniture, fixtures and office equipment Furniture and Fixtures [Member] Computer equipment and software Computer Equipment [Member] Leasehold improvements Leasehold Improvements [Member] Construction in process Construction in Progress [Member] Property and equipment, net: Property, Plant and Equipment [Line Items] Total property and equipment, gross Property, Plant and Equipment, Gross Less: Accumulated depreciation Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Total, net Depreciation and amortization Depreciation, Depletion and Amortization, Excluding Intangible Assets Depreciation, Depletion and Amortization, Excluding Intangible Assets Class of Warrant or Right [Table] Class of Warrant or Right [Table] Class of Warrant or Right [Axis] Class of Warrant or Right [Axis] Class of Warrant or Right [Domain] Class of Warrant or Right [Domain] August 2013 Warrants Warrants Issued In August2013 [Member] Represents the warrants issued by the entity in August 2013. September 2016 Warrants Warrants Issued In September 2016 [Member] Warrants Issued In September 2016 [Member] Stock Purchase Warrants Class of Warrant or Right [Line Items] Total shares issuable on exercise (in shares) Class of Warrant or Right, Number of Securities Called by Warrants or Rights Warrants issued (in shares) Class of Warrant or Right, Warrants Issued Class of Warrant or Right, Warrants Issued Number of warrant holders Class of Warrant or Right, Number of Holders Class of Warrant or Right, Number of Holders Assumptions used in calculating the estimated fair value of the warrants Fair Value Assumptions and Methodology for Assets and Liabilities [Abstract] Closing stock price (in dollars per share) Share Price Expected dividend rate Fair Value Assumptions, Expected Dividend Rate Expected stock price volatility Fair Value Assumptions, Expected Volatility Rate Risk-free interest rate Fair Value Assumptions, Risk Free Interest Rate Expected life Fair Value Assumptions, Expected Term DEBT Debt Disclosure [Text Block] Incentive from Lessor Incentive from Lessor Deferred rent credit Deferred Rent Credit Operating leases Operating Leases Leased Office Space Future Minimum Payments Due [Abstract] Total Operating Leases, Future Minimum Payments Due 2017 Operating Leases, Future Minimum Payments, Remainder of Fiscal Year 2018 Operating Leases, Future Minimum Payments, Due in Two Years 2019 Operating Leases, Future Minimum Payments, Due in Three Years 2020 Operating Leases, Future Minimum Payments, Due in Four Years 2021 Operating Leases, Future Minimum Payments, Due in Five Years More than 5 Years Operating Leases, Future Minimum Payments, Due Thereafter Purchase commitments Purchase Obligation, Fiscal Year Maturity [Abstract] Total Purchase Obligation 2017 Purchase Obligation, Due in Next Twelve Months 2018 Purchase Obligation, Due in Second Year 2019 Purchase Obligation, Due in Third Year 2020 Purchase Obligation, Due in Fourth Year 2021 Purchase Obligation, Due in Fifth Year More than 5 Years Purchase Obligation, Due after Fifth Year Capital leases Operating Leases Sales Force Leased Auto Fleet Future Minimum Payments Due [Abstract] Total Capital Lease Obligations 2017 Capital Leases, Future Minimum Payments Due, Next Twelve Months 2018 Capital Leases, Future Minimum Payments Due in Two and Three Years 2019 Capital Leases, Future Minimum Payments Due in Three Years 2020 Capital Leases, Future Minimum Payments Due in Four Years 2021 Capital Leases, Future Minimum Payments Due in Five Years More than 5 Years Capital Leases, Future Minimum Payments Due Thereafter Total Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract] Total Operating and Capital Leases and Purchase Commitments, Future Minimum Payments Due Operating and Capital Leases and Purchase Commitments, Future Minimum Payments Due 2017 Operating and Capital Leases and Purchase Commitments, Future Minimum Payments Due, Current Operating and Capital Leases and Purchase Commitments, Future Minimum Payments Due, Current 2018 Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due In Two Years Operating and Capital Leases and Purchase Commitments, Due In Two Years 2019 Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due In Three Years Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due In Three Years 2020 Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due In Four Years Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due In Four Years 2021 Minimum Lease Payments, Sale Leaseback Transactions, Due in Rolling after Year Five More than 5 Years Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due Thereafter Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due Thereafter Rent expense Operating Leases, Rent Expense, Net Income Statement [Abstract] Product sales, net Sales Revenue, Goods, Net Cost of product sales Cost of Goods Sold Gross profit Gross Profit Research and development Research and Development Expense Selling, general and administrative Selling, General and Administrative Expense Total operating expenses Operating Expenses Loss from operations Operating Income (Loss) Other income (expense): Other Nonoperating Income (Expense) [Abstract] (Increase) decrease in fair value of warrants Foreign currency translation loss Foreign Currency Transaction Gain (Loss), Realized Interest income Investment Income, Interest Interest expense Interest Expense Other income (expense) Other Nonoperating Income (Expense) Total other income (expense) Nonoperating Income (Expense) Net loss Net loss per share attributable to common shareholders (Basic and Diluted) (see note 12) (in dollars per share) Weighted average number of common shares outstanding (Basic and Diluted) (in shares) Fair Value Measurements, Recurring and Nonrecurring [Table] Fair Value Measurements, Recurring and Nonrecurring [Table] Warrants Warrant [Member] Measurement Frequency [Axis] Measurement Frequency [Axis] Fair Value, Measurement Frequency [Domain] Fair Value, Measurement Frequency [Domain] Recurring Fair Value, Measurements, Recurring [Member] Fair Value, Hierarchy [Axis] Fair Value, Hierarchy [Axis] Fair Value Hierarchy [Domain] Fair Value Hierarchy [Domain] Level 2 Fair Value, Inputs, Level 2 [Member] Level 3 Fair Value, Inputs, Level 3 [Member] Liabilities that are measured at fair value on a recurring basis Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Change in the estimated fair value of warrant liabilities Warrants and Rights [Roll Forward] A roll forward is a reconciliation of a concept from the beginning of a period to the end of the period. Balance at December 31, 2016 Increase in fair value Balance at September 30, 2017 Lines of credit, fair value Lines of Credit, Fair Value Disclosure