Accumulated Amortization
Finite-Lived Intangible Assets, Accumulated Amortization
Statistical Measurement [Domain]
Statistical Measurement [Domain]
Schedule of fair value of securities, not including cash
Debt Securities, Available-for-Sale [Table Text Block]
Directly to consumer
Sales Channel, Directly to Consumer [Member]
Award Timing Predetermined
Award Timing Predetermined [Flag]
Base period maximum funding
Collaborative Arrangement, Base Period Maximum Funding
Collaborative Arrangement, Base Period Maximum Funding
Sales threshold for first milestone
License Agreement, Initial Milestone, Sales
License Agreement, Initial Milestone, Sales
Entity File Number
Entity File Number
Milestone payments, assumed intangible assets
License Agreements, Milestone Payments, Assumed Intangible Assets
License Agreements, Milestone Payments, Assumed Intangible Assets
Tabular List, Table
Tabular List [Table Text Block]
Leases [Abstract]
Leases [Abstract]
Recent Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Purchases of investments
Payments to Acquire Short-Term Investments
Accounts payable
Increase (Decrease) in Accounts Payable
SOFR
Secured Overnight Financing Rate (SOFR) [Member]
Restricted stock withheld for employee tax remittance
Share-Based Payment Arrangement, Decrease for Tax Withholding Obligation
Gross Unrealized Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Trading Arrangements, by Individual
Trading Arrangements, by Individual [Table]
Basic (in USD per share)
Basic loss per common share (in USD per share)
Earnings Per Share, Basic
Adjustment to Compensation:
Adjustment to Compensation [Axis]
Named Executive Officers, Footnote
Named Executive Officers, Footnote [Text Block]
Commercial paper
Commercial Paper [Member]
Revenue
Revenue from Contract with Customer [Text Block]
Number of specialty pharmacies
Number of Contracted Specialty Pharmacies
Number of Contracted Specialty Pharmacies
Schedule disaggregated amounts that comprise selling, general and administrative expenses
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Issuance of stock for restricted stock unit vesting (in shares)
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures
Shares issued under the Employee Stock Purchase Plan (in shares)
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Area of real estate property
Area of Real Estate Property
Term of supply agreement
License Agreement, Supply Agreement Term
License Agreement, Supply Agreement Term
Adjustment to Compensation, Amount
Adjustment to Compensation Amount
Stock-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Stock options
Share-Based Payment Arrangement, Option [Member]
Award Timing MNPI Disclosure
Award Timing MNPI Disclosure [Text Block]
Property, Plant and Equipment [Table]
Property, Plant and Equipment [Table]
Cash and cash equivalents
Cash and Cash Equivalents [Member]
Finance Lease, Liability, Noncurrent, Statement of Financial Position [Extensible List]
Finance Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]
Antidilutive Securities [Axis]
Antidilutive Securities [Axis]
Impairments of assets
Asset Impairment Charges
Total shareholders’ equity
Beginning balance
Ending balance
Equity, Attributable to Parent
Measurement Frequency [Axis]
Measurement Frequency [Axis]
Insider Trading Policies and Procedures [Line Items]
Total non-cash stock-based compensation expense
Share-Based Payment Arrangement, Expense
Schedule of property and equipment, net
Property, Plant and Equipment [Table Text Block]
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized
Finance Lease, Liability, Current, Statement of Financial Position [Extensible List]
Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Current assets:
Assets, Current [Abstract]
Total liabilities and shareholders’ equity
Liabilities and Equity
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Recurring
Fair Value, Recurring [Member]
Leverage ratio
Debt Instrument, Covenant, Leverage Ratio, Maximum
Debt Instrument, Covenant, Leverage Ratio, Maximum
Licensing Agreements
Licensing Agreements [Member]
LIABILITIES AND SHAREHOLDERS’ EQUITY
Liabilities and Equity [Abstract]
Other income (expense):
Other Nonoperating Income (Expense) [Abstract]
Cover [Abstract]
Cover [Abstract]
Money market funds
Cash and Cash Equivalents, Fair Value Disclosure
Maximum
Maximum [Member]
Contract value
Collaborative Arrangement, Contract Value
Collaborative Arrangement, Contract Value
Useful Life (in years)
Finite-Lived Intangible Asset, Useful Life
Accounting Policies [Abstract]
Accounting Policies [Abstract]
Intangible assets, net
Total
Finite-Lived Intangible Assets, Net
Non-PEO NEO Average Total Compensation Amount
Non-PEO NEO Average Total Compensation Amount
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Adjustment to Non-PEO NEO Compensation Footnote
Adjustment to Non-PEO NEO Compensation Footnote [Text Block]
Pay vs Performance Disclosure [Line Items]
U.S. government agency bonds
US Government Agencies Debt Securities [Member]
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Liabilities
Liabilities [Abstract]
Non-Rule 10b5-1 Arrangement Terminated
Non-Rule 10b5-1 Arrangement Terminated [Flag]
Entity Shell Company
Entity Shell Company
Other long-term liabilities
Other Liabilities, Noncurrent
Schedule of Long-term Debt Instruments [Table]
Schedule of Long-Term Debt Instruments [Table]
Epicel
Epicel [Member]
Epicel [Member]
Statement of Stockholders' Equity [Abstract]
Statement of Stockholders' Equity [Abstract]
Statement of Cash Flows [Abstract]
Statement of Cash Flows [Abstract]
Company Selected Measure Amount
Company Selected Measure Amount
Award Timing MNPI Considered
Award Timing MNPI Considered [Flag]
Bonus-related compensation
Accrued Bonuses, Current
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Name
Measure Name
Letter of credit
Letter of Credit [Member]
Schedule of non-cash stock-based compensation expense
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Current portion of operating lease liabilities
Operating
Operating Lease, Liability, Current
Finance lease expense (less than)
Finance Lease, Interest Expense
Document Fiscal Period Focus
Document Fiscal Period Focus
Contract term (in years)
Collaborative Arrangement, Contract Term
Collaborative Arrangement, Contract Term
Award Timing Method
Award Timing Method [Text Block]
Furniture, fixtures and office equipment
Furniture and Fixtures [Member]
Award Type [Axis]
Award Type [Axis]
Total assets
Assets
Investing activities:
Cash Provided by (Used in) Investing Activity, Continuing Operation [Abstract]
2027
Finite-Lived Intangible Asset, Expected Amortization, Year One
Trading Symbol
Trading Symbol
Entity Address, City or Town
Entity Address, City or Town
Marketable Securities [Line Items]
Marketable Securities [Line Items]
Change in revenue recognized due to 0.5% change in uncollectible percentage
Revenue, Revenue Recognized, Effect Of 0.5% Change In The Estimated Uncollectible Percentage, Amount
Revenue, Revenue Recognized, Effect Of 0.5% Change In The Estimated Uncollectible Percentage, Amount
Non-PEO NEO Average Compensation Actually Paid Amount
Non-PEO NEO Average Compensation Actually Paid Amount
Restricted stock units
Restricted Stock Units (RSUs) [Member]
Income Statement Location [Domain]
Statement of Income Location, Balance [Domain]
Compensation Actually Paid vs. Other Measure
Compensation Actually Paid vs. Other Measure [Text Block]
2030
Finite-Lived Intangible Asset, Expected Amortization, Year Four
Entity Emerging Growth Company
Entity Emerging Growth Company
Purchases of intangible assets
Payments to Acquire Intangible Assets
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Computer equipment and software
Computer Equipment And Computer Software Intangible Asset [Member]
Long lived, depreciable assets that are used in the creation, maintenance and utilization of information systems and the collection of computer programs and related data that provide instructions to a computer, for example, but not limited to, application program, control module or operating system, that perform one or more particular functions or tasks.
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member]
Debt issuance costs, net
Debt Issuance Costs, Net
Level 2
Fair Value, Inputs, Level 2 [Member]
Insurance reimbursement-related liabilities
Accrued Insurance, Current
Insider Trading Policies and Procedures Not Adopted
Insider Trading Policies and Procedures Not Adopted [Text Block]
Basis of Presentation
Basis of Accounting [Text Block]
Common stock, shares outstanding (in shares)
Beginning balance (in shares)
Ending balance (in shares)
Common Stock, Shares, Outstanding
Thereafter
Finite-Lived Intangible Asset, Expected Amortization, after Year Four
Finite-Lived Intangible Asset, Expected Amortization, after Year Four
PEO
PEO [Member]
Schedule of disaggregation of revenue
Disaggregation of Revenue [Table Text Block]
Sales and maturities of investments
Proceeds from Sale, Maturity and Collection of Investments
Interest income
Investment Income, Interest
Changes in operating assets and liabilities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Stock option exercises
Stock Issued During Period, Value, Stock Options Exercised
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member]
Schedule of finite-lived intangible assets, future amortization expense
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
Accumulated Deficit
Retained Earnings [Member]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Restatement Determination Date
Restatement Determination Date
Share-based Payment Arrangement [Abstract]
Share-Based Payment Arrangement [Abstract]
Cash, cash equivalents, and restricted cash at beginning of period
Cash, cash equivalents, and restricted cash at end of period
Total cash, cash equivalents, and restricted cash at end of period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Income Statement [Abstract]
Income Statement [Abstract]
Basis spread on variable rate (in percent)
Debt Instrument, Basis Spread on Variable Rate
Pension Adjustments Service Cost
Pension Adjustments Service Cost [Member]
Product and Service [Domain]
Product and Service [Domain]
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV [Axis]
Restatement does not require Recovery
Restatement Does Not Require Recovery [Text Block]
Total liabilities
Liabilities, Fair Value Disclosure
Allowance for doubtful accounts
Allowance for Credit Loss, Receivable, Other, Current
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Other current assets
Increase (Decrease) in Other Current Assets
Non-cash lease costs
Operating Lease, Right-of-Use Asset, Periodic Reduction
Compensation Actually Paid vs. Company Selected Measure
Compensation Actually Paid vs. Company Selected Measure [Text Block]
Renewal term of supply agreement
License Agreement, Supply Agreement Renewal Term
License Agreement, Supply Agreement Renewal Term
Number of commercial-stage products
Number Of Products
Number Of Products
Less accumulated depreciation
Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, Accumulated Depreciation and Amortization
City Area Code
City Area Code
Award Timing, How MNPI Considered
Award Timing, How MNPI Considered [Text Block]
All Trading Arrangements
All Trading Arrangements [Member]
Equity Awards Adjustments, Footnote
Equity Awards Adjustments, Footnote [Text Block]
Total Shareholder Return Vs Peer Group
Total Shareholder Return Vs Peer Group [Text Block]
Accrued expenses
Total accrued expenses
Accrued Liabilities, Current
Supply agreement additional term
License Agreement, Supply Agreement, Optional Additional Term
License Agreement, Supply Agreement, Optional Additional Term
Commitments and Contingencies Disclosure [Abstract]
Commitments and Contingencies Disclosure [Abstract]
General and administrative
General and Administrative Expense
Pay vs Performance Disclosure
Pay vs Performance Disclosure [Table]
Net cash provided by operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Debt instrument, term
Debt Instrument, Term
Related Party Transactions [Abstract]
Related Party Transactions [Abstract]
Selling, general and administrative
Selling, General and Administrative Expenses [Member]
Cost of product sales
Cost of Sales [Member]
Operating lease liabilities
Increase (Decrease) In Lease Liabilities
Increase (Decrease) In Lease Liabilities
Equity Valuation Assumption Difference, Footnote
Equity Valuation Assumption Difference, Footnote [Text Block]
PEO Total Compensation Amount
PEO Total Compensation Amount
Long-Term Debt, Type [Axis]
Long-Term Debt, Type [Axis]
Depreciation
Depreciation
Money market funds
Money Market Funds [Member]
Remainder of 2026
Finite-Lived Intangible Asset, Expected Amortization, Remainder of Fiscal Year
U.S. Biomedical Advanced Research and Development Authority (BARDA)
U.S. Biomedical Advanced Research and Development Authority (BARDA) [Member]
U.S. Biomedical Advanced Research and Development Authority (BARDA)
Equity Components [Axis]
Equity Components [Axis]
Property and equipment, net:
Property, Plant and Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Organization
Nature of Operations [Text Block]
Non-Rule 10b5-1 Arrangement Adopted
Non-Rule 10b5-1 Arrangement Adopted [Flag]
Number of reportable segments
Number of Reportable Segments
Contract with Customer, Basis of Pricing [Axis]
Contract with Customer, Basis of Pricing [Axis]
Supplemental disclosure of cash flow information:
Supplemental Cash Flow Information [Abstract]
Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Other Performance Measure, Amount
Other Performance Measure, Amount
Entity Address, State or Province
Entity Address, State or Province
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Antidilutive Security, Excluded EPS Calculation [Table]
Total current liabilities
Liabilities, Current
Individual:
Individual [Axis]
Total property and equipment, gross
Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, before Accumulated Depreciation and Amortization
Leases
Lessee, Finance Leases [Text Block]
Other current assets
Other Assets, Current
Research and development
Research and Development Expense [Member]
25 Network Drive, Burlington, Massachusetts
25 Network Drive, Burlington, Massachusetts [Member]
25 Network Drive, Burlington, Massachusetts Member
Effect of Change in Accounting Estimate, Type [Axis]
Effect of Change in Accounting Estimate, Type [Axis]
Net cash used in investing activities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member]
Document Fiscal Year Focus
Document Fiscal Year Focus
Right-of-use assets
Operating
Operating Lease, Right-of-Use Asset
Forgone Recovery, Explanation of Impracticability
Forgone Recovery, Explanation of Impracticability [Text Block]
MACI implants, kits, and instruments
Implants [Member]
Implants [Member]
Entity Interactive Data Current
Entity Interactive Data Current
Operating activities:
Cash Provided by (Used in) Operating Activity, Continuing Operation [Abstract]
Stock option exercises (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Segment Information
Segment Reporting Disclosure [Text Block]
Liabilities that are measured at fair value on a recurring basis
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Disaggregation of Revenue [Table]
Disaggregation of Revenue [Table]
Property, Plant and Equipment, Type [Axis]
Long-Lived Tangible Asset [Axis]
Increase (Decrease) in Shareholders' Equity
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Finite-Lived Intangible Assets [Line Items]
Finite-Lived Intangible Assets [Line Items]
Compensation Actually Paid vs. Total Shareholder Return
Compensation Actually Paid vs. Total Shareholder Return [Text Block]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value, Recurring and Nonrecurring [Table]
Amortization of intangible assets
Amortization of Intangible Assets
Selling, general and administrative
Total selling, general and administrative expenses
Selling, General and Administrative Expense
Depreciation and amortization expense
Depreciation, Depletion and Amortization
Other long-term assets
Other Assets, Noncurrent
Entity Central Index Key
Entity Central Index Key
PEO Name
PEO Name
Total revenue
Revenues
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member]
Finished goods
Inventory, Finished Goods, Gross
Outstanding Aggregate Erroneous Compensation Amount
Outstanding Aggregate Erroneous Compensation Amount
Contract rate
Fixed-Price Contract [Member]
Revolving credit facility
Revolving Credit Facility [Member]
Arrangement Duration
Trading Arrangement Duration
NexoBrid
NexoBrid [Member]
NexoBrid
Exercise Price
Award Exercise Price
Entity Filer Category
Entity Filer Category
Local Phone Number
Local Phone Number
Additional 402(v) Disclosure
Additional 402(v) Disclosure [Text Block]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Stock-Based Compensation
Share-Based Payment Arrangement [Text Block]
ASSETS
Assets
Assets [Abstract]
Credit Facility [Axis]
Credit Facility [Axis]
Underlying Security Market Price Change
Underlying Security Market Price Change, Percent
Remaining contractual maturity period
Debt Securities, Available-for-sale, Contractual Maturity Period
Debt Securities, Available-for-sale, Contractual Maturity Period
Balance Sheet Location [Axis]
Statement of Financial Position Location, Balance [Axis]
2029
Finite-Lived Intangible Asset, Expected Amortization, Year Three
Fair Value Measurements
Fair Value Disclosures [Text Block]
Credit Facility [Domain]
Credit Facility [Domain]
Cost
Finite-Lived Intangible Assets, Gross
Shareholders’ equity:
Equity, Attributable to Parent [Abstract]
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member]
Entity Address, Address Line One
Entity Address, Address Line One
Research and development
Research and Development Expense
Accumulated Other Comprehensive Gain (Loss)
AOCI Attributable to Parent [Member]
Allowance for doubtful accounts
Accounts Receivable, Allowance for Credit Loss, Current
Restricted stock withheld for employee tax remittance (in shares)
Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation
Operating lease liabilities
Operating
Operating Lease, Liability, Noncurrent
Balance Sheet Related Disclosures [Abstract]
Balance Sheet Related Disclosures [Abstract]
Work-in-process
Inventory, Work in Process, Gross
Name of Property [Domain]
Name of Property [Domain]
Fair Value as of Grant Date
Award Grant Date Fair Value
Initial procurement funds
Collaborative Arrangement, Initial Procurement Funds
Collaborative Arrangement, Initial Procurement Funds
Entity Registrant Name
Entity Registrant Name
Other accrued expenses
Accrued Expenses, Other, Current
Represents other accrued expenses, current.
Stock Price or TSR Estimation Method
Stock Price or TSR Estimation Method [Text Block]
Deferred compensation plan liabilities
Deferred Compensation Liability, Current and Noncurrent
Effect of dilutive stock options and restricted stock units (in shares)
Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements
Restricted stock units granted (shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Document Quarterly Report
Document Quarterly Report
Assets, fair value
Assets, Fair Value Disclosure
Changed Peer Group, Footnote
Changed Peer Group, Footnote [Text Block]
Counterparty Name [Domain]
Counterparty Name [Domain]
Cost, Product and Service [Extensible List]
Cost, Product and Service [Extensible Enumeration]
Amortization of premiums and discounts on marketable securities
Accretion (Amortization) of Discounts and Premiums, Investments
Adjustment To PEO Compensation, Footnote
Adjustment To PEO Compensation, Footnote [Text Block]
Schedule of accrued expenses
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Machinery and equipment
Machinery and Equipment [Member]
Restricted stock units weighted-average grant date fair value (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Investments
Investments
Title
Trading Arrangement, Individual Title
Peer Group Total Shareholder Return Amount
Peer Group Total Shareholder Return Amount
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Schedule of finite-lived intangible assets
Schedule of Finite-Lived Intangible Assets [Table Text Block]
Restatement Determination Date:
Restatement Determination Date [Axis]
Non-PEO NEO
Non-PEO NEO [Member]
Issuance of letters of credit
Letters of Credit Outstanding, Amount
Credit Losses
Debt Securities, Available-for-Sale, Allowance for Credit Loss
Shares issued under the Employee Stock Purchase Plan
Stock Issued During Period, Value, Employee Stock Purchase Plan
Other
Proceeds from (Payment for) Other Financing Activity
Schedule of valuation of the company's investments and financial instruments that are measured at fair value on a recurring basis
Fair Value, Liabilities Measured on Recurring Basis [Table Text Block]
Gross Unrealized Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Name
Trading Arrangement, Individual Name
Award Type [Domain]
Award Type [Domain]
Contract with Customer, Basis of Pricing [Domain]
Contract with Customer, Basis of Pricing [Domain]
Increase option for leverage ratio
Debt Instrument, Covenant, Increase Option, Leverage Ratio, Maximum
Debt Instrument, Covenant, Increase Option, Leverage Ratio, Maximum
Equity Awards Adjustments
Equity Awards Adjustments [Member]
Leasehold improvements
Leasehold Improvements [Member]
Other
Other Noncash Income (Expense)
Pension Benefits Adjustments, Footnote
Pension Benefits Adjustments, Footnote [Text Block]
Disaggregation of Revenue [Line Items]
Disaggregation of Revenue [Line Items]
Compensation Amount
Outstanding Recovery Compensation Amount
Statement of Comprehensive Income [Abstract]
Statement of Comprehensive Income [Abstract]
Recovery of Erroneously Awarded Compensation Disclosure [Line Items]
MNPI Disclosure Timed for Compensation Value
MNPI Disclosure Timed for Compensation Value [Flag]
Name
Awards Close in Time to MNPI Disclosures, Individual Name
Aggregate Erroneous Compensation Not Yet Determined
Aggregate Erroneous Compensation Not Yet Determined [Text Block]
Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible List]
Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
Accumulated other comprehensive (loss) gain
Accumulated Other Comprehensive Income (Loss), Net of Tax
Selling and marketing
Selling and Marketing Expense
Financial Instruments [Domain]
Financial Instruments [Domain]
Income Statement Location [Axis]
Statement of Income Location, Balance [Axis]
Investments
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Aggregate Pension Adjustments Service Cost
Aggregate Pension Adjustments Service Cost [Member]
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV [Domain]
Balance Sheet Location [Domain]
Statement of Financial Position Location, Balance [Domain]
Inventory
Increase (Decrease) in Inventories
Inventory
Total inventory
Inventory, Net
Finite-Lived Intangible Assets by Major Class [Axis]
Finite-Lived Intangible Assets by Major Class [Axis]
Minimum
Minimum [Member]
Through Intermediary
Sales Channel, Through Intermediary [Member]
Company Selected Measure Name
Company Selected Measure Name
U.S. government securities
US Government Debt Securities [Member]
Revolving Credit Agreement
Debt Disclosure [Text Block]
Aggregate Available
Trading Arrangement, Securities Aggregate Available Amount
Accounts payable
Accounts Payable, Current
Stock Appreciation Rights (SARs)
Stock Appreciation Rights (SARs) [Member]
All Executive Categories
All Executive Categories [Member]
Common stock, no par value; shares authorized — 75,000; shares issued and outstanding — 51,010 and 50,620, respectively
Common Stock, Value, Issued
Finance
Finance Lease, Right-of-Use Asset, after Accumulated Amortization
Schedule of assets and liabilities
Assets And Liabilities, Leases [Table Text Block]
Assets And Liabilities, Leases [Table Text Block]
Short-term investments
Short-Term Investments
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Diluted (in shares)
Diluted weighted-average common shares outstanding (in shares)
Weighted Average Number of Shares Outstanding, Diluted
COMMITMENTS AND CONTINGENCIES (Note 12)
Commitments and Contingencies
Non-GAAP Measure Description
Non-GAAP Measure Description [Text Block]
NexoBrid
Revenue Not from Contract with Customer, Other
Entity Small Business
Entity Small Business
Revenue, Product and Service [Extensible List]
Revenue, Product and Service [Extensible Enumeration]
Document Transition Report
Document Transition Report
Short-term investments
Short-Term Investments [Member]
Underlying Securities
Award Underlying Securities Amount
Corporate notes
Corporate Note Securities [Member]
Equity Component [Domain]
Equity Component [Domain]
Document Period End Date
Document Period End Date
PEO Actually Paid Compensation Amount
PEO Actually Paid Compensation Amount
Cash and Cash Equivalents [Domain]
Cash and Cash Equivalents [Domain]
Selected Balance Sheet Components
Supplemental Balance Sheet Disclosures [Text Block]
Awards Close in Time to MNPI Disclosures, Table
Awards Close in Time to MNPI Disclosures [Table Text Block]
Revenue from Contract with Customer [Abstract]
Revenue from Contract with Customer [Abstract]
Short-term lease costs (less than)
Short-Term Lease, Cost
Document Type
Document Type
Level 3
Fair Value, Inputs, Level 3 [Member]
Net Income (Loss) Per Common Share
Earnings Per Share [Text Block]
Name
Outstanding Recovery, Individual Name
Marketable Securities [Table]
Marketable Securities [Table]
Total leased assets
Right Of Use Asset
Right Of Use Asset
Product and Service [Axis]
Product and Service [Axis]
Net proceeds from common stock issuance
Proceeds from Issuance of Common Stock
Product sales, net
Revenue from Contract with Customer, Excluding Assessed Tax
All Individuals
All Individuals [Member]
Long-Term Debt, Type [Domain]
Long-Term Debt, Type [Domain]
Effect of Change in Accounting Estimate, Type [Domain]
Effect of Change in Accounting Estimate, Type [Domain]
Fair Value Disclosures [Abstract]
Fair Value Disclosures [Abstract]
Accounts receivable
Increase (Decrease) in Receivables
Expenditures for property and equipment
Payments to Acquire Property, Plant, and Equipment
Name
Forgone Recovery, Individual Name
Total current assets
Assets, Current
Statistical Measurement [Axis]
Statistical Measurement [Axis]
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member]
Reconciliation to amounts within the condensed consolidated balance sheets:
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation [Abstract]
Aggregate Erroneous Compensation Amount
Aggregate Erroneous Compensation Amount
Payments on employees’ behalf for taxes related to vesting of restricted stock unit awards
Payment, Tax Withholding, Share-Based Payment Arrangement
Peer Group Issuers, Footnote
Peer Group Issuers, Footnote [Text Block]
Accrued expenses
Accrued Liabilities, Current [Abstract]
Erroneous Compensation Analysis
Erroneous Compensation Analysis [Text Block]
Total leased liabilities
Lease Liability Noncurrent
Lease Liability Noncurrent
Schedule of Finite-Lived Intangible Assets [Table]
Intangible Asset, Finite-Lived [Table]
Unrealized (loss) gain on investments
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent
Current liabilities:
Current
Liabilities, Current [Abstract]
Lessee, Lease, Description [Line Items]
Lessee, Lease, Description [Line Items]
Total operating expenses
Operating Expenses
Rule 10b5-1 Arrangement Terminated
Rule 10b5-1 Arrangement Terminated [Flag]
Outstanding borrowings
Long-Term Line of Credit
Level 1
Fair Value, Inputs, Level 1 [Member]
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Accrued expenses
Increase (Decrease) in Accrued Liabilities
Schedule of Related Party Transactions, by Related Party [Table]
Related Party Transaction [Table]
Diluted (in USD per share)
Diluted loss per common share (in USD per share)
Earnings Per Share, Diluted
Erroneously Awarded Compensation Recovery
Erroneously Awarded Compensation Recovery [Table]
Accounts receivable (net of allowance for doubtful accounts of $13 and $13, respectively)
Accounts Receivable, after Allowance for Credit Loss, Current
Title of 12(b) Security
Title of 12(b) Security
Lessee, Lease, Description [Table]
Lessee, Lease, Description [Table]
Change in estimate of uncollectible (percent)
Revenue, Revenue Recognized, Change in Uncollectible Analysis, Percentage
Revenue, Revenue Recognized, Change in Uncollectible Analysis, Percentage
Other comprehensive income (loss):
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract]
Net loss per common share:
Earnings Per Share [Abstract]
Total other income
Nonoperating Income (Expense)
Contract with Customer, Sales Channel [Domain]
Contract with Customer, Sales Channel [Domain]
Investments, Debt and Equity Securities [Abstract]
Restricted stock held for employee tax remittance included in accounts payable
Restricted Stock Held For Employee Tax Remittance Included In Accounts Payable
Restricted Stock Held For Employee Tax Remittance Included In Accounts Payable
Gross profit
Gross Profit
Contract with Customer, Sales Channel [Axis]
Contract with Customer, Sales Channel [Axis]
Change in estimates related to prior periods
Change in Accounting Method Accounted for as Change in Estimate [Member]
2028
Finite-Lived Intangible Asset, Expected Amortization, Year Two
Award Timing Disclosures [Line Items]
Schedule of inventory
Schedule of Inventory, Current [Table Text Block]
Measurement Frequency [Domain]
Measurement Frequency [Domain]
Employee-related accruals
Employee-related Liabilities, Current
Property and equipment, net
Total property and equipment, net
Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, after Accumulated Depreciation and Amortization
Net loss
Net loss
Net loss
Net loss
Net Income (Loss) Attributable to Parent
Expiration Date
Trading Arrangement Expiration Date
Non-current
Liabilities, Noncurrent [Abstract]
Construction in process
Construction in Progress [Member]
Other non-current assets and liabilities, net
Increase (Decrease) in Other Operating Liabilities
Net Income (Loss) Attributable to Parent [Abstract]
Net Income (Loss) Attributable to Parent [Abstract]
Adoption Date
Trading Arrangement Adoption Date
Base rate
Base Rate [Member]
Compensation Actually Paid vs. Net Income
Compensation Actually Paid vs. Net Income [Text Block]
Entity Current Reporting Status
Entity Current Reporting Status
Awards Close in Time to MNPI Disclosures
Awards Close in Time to MNPI Disclosures [Table]
Financing activities:
Cash Provided by (Used in) Financing Activity, Continuing Operation [Abstract]
Loss from operations
Operating Income (Loss)
Line of credit
Line of Credit [Member]
Accumulated deficit
Accumulated Deficit
Retained Earnings (Accumulated Deficit)
Name of Property [Axis]
Name of Property [Axis]
Biopsy kits
Biopsy Kits [Member]
Biopsy Kits [Member]
Financial Instrument [Axis]
Financial Instrument [Axis]
Statement of Financial Position [Abstract]
Statement of Financial Position [Abstract]
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member]
Executive Category:
Executive Category [Axis]
Finance
Finance Lease, Liability, Current
Current Fiscal Year End Date
Current Fiscal Year End Date
Finite-Lived Intangible Assets, Major Class Name [Domain]
Finite-Lived Intangible Assets, Major Class Name [Domain]
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member]
Maximum contingent consideration
License Agreement, Contingent Consideration, Maximum
License Agreement, Contingent Consideration, Maximum
Statement [Table]
Statement [Table]
Other income
Other Nonoperating Income (Expense)
Adjustments to reconcile net loss to net cash flows from operating activities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
The BARDA Agreement
Collaborative Arrangement Disclosure [Text Block]
Stock options weighted average grant-date fair value (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Equity Awards Adjustments, Excluding Value Reported in Compensation Table
Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member]
Variable Rate [Domain]
Variable Rate [Domain]
MediWound Ltd
MediWound Ltd [Member]
MediWound Ltd [Member]
Finance
Finance Lease, Liability, Noncurrent
Anti-dilutive shares excluded from the calculation of diluted earnings per share (in shares)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Weighted-average common shares outstanding:
Anti-dilutive shares excluded from diluted net loss per common share:
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
All Adjustments to Compensation
All Adjustments to Compensation [Member]
Amendment Flag
Amendment Flag
Employee stock purchase plan and service-based stock options
Employee Stock And Employee Stock Option [Member]
Employee Stock And Employee Stock Option [Member]
Leases
Lessee, Operating Leases [Text Block]
Termination Date
Trading Arrangement Termination Date
Net cash (used in) provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Insider Trading Policies and Procedures Adopted
Insider Trading Policies and Procedures Adopted [Flag]
Measure:
Measure [Axis]
Long-term investments
Long-term Investments [Member]
Long-term Investments [Member]
Long-term investments
Debt Securities, Available-for-Sale, Noncurrent
Property, Plant and Equipment, Type [Domain]
Long-Lived Tangible Asset [Domain]
Basic (in shares)
Basic weighted-average common shares outstanding (in shares)
Weighted Average Number of Shares Outstanding, Basic
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Provision for excess and obsolete inventory
Inventory Write-down
Cost of product sales
Cost of Product and Service Sold
Schedule of net income (loss) per common share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Restricted cash
Restricted Cash and Cash Equivalent, Noncurrent
Segment Reporting [Abstract]
Pay vs Performance Disclosure, Table
Pay vs Performance [Table Text Block]
Operating lease expense
Operating Lease, Expense
Debt Disclosure [Abstract]
Debt Disclosure [Abstract]
Forgone Recovery due to Violation of Home Country Law, Amount
Forgone Recovery due to Violation of Home Country Law, Amount
M A C I Implants and kits
MACI Implants And Kits [Member]
MACI Implants And Kits
Amortization of debt issuance costs
Amortization of Debt Issuance Costs
Entity Tax Identification Number
Entity Tax Identification Number
Contingent consideration
License Agreement, Contingent Consideration
License Agreement, Contingent Consideration
Inventory:
Inventory, Net [Abstract]
Forgone Recovery due to Expense of Enforcement, Amount
Forgone Recovery due to Expense of Enforcement, Amount
Stock-Based Compensation
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Common stock, shares issued (in shares)
Common Stock, Shares, Issued
Stock options granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Consideration payment for license
License Agreement, Consideration
License Agreement, Consideration
Provider or Facility
Provider or Facility [Member]
Provider or Facility [Member]
Interest expense
Interest Expense, Nonoperating
Trading Arrangement:
Trading Arrangement [Axis]
Total Shareholder Return Amount
Total Shareholder Return Amount
Insider Trading Arrangements [Line Items]
Security Exchange Name
Security Exchange Name
Raw materials
Inventory, Raw Materials, Gross
Total liabilities
Liabilities
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name [Domain]
Cash and Cash Equivalents [Axis]
Cash and Cash Equivalents [Axis]
Line of credit facility, commitment fee (in percent)
Line of Credit Facility, Commitment Fee Percentage
Additions to property and equipment included in accounts payable
Capital Expenditures Incurred but Not yet Paid
Maximum borrowing capacity
Line of Credit Facility, Maximum Borrowing Capacity
NexoBrid License and Supply Agreements
License Agreement [Text Block]
License Agreement [Text Block]
Pension Adjustments Prior Service Cost
Pension Adjustments Prior Service Cost [Member]
Material Terms of Trading Arrangement
Material Terms of Trading Arrangement [Text Block]
Other current liabilities
Other Liabilities, Current
Time-and-materials contract
Time-and-Materials Contract [Member]
Stock-based compensation expense
Shares Granted, Value, Share-Based Payment Arrangement, after Forfeiture
Statement
Statement [Line Items]
Variable Rate [Axis]
Variable Rate [Axis]
Rule 10b5-1 Arrangement Adopted
Rule 10b5-1 Arrangement Adopted [Flag]
Cash and cash equivalents
Cash and Cash Equivalent
Counterparty Name [Axis]
Counterparty Name [Axis]
Common Stock
Common Stock [Member]
Estimated Fair Value
Debt securities, fair value
Debt Securities, Available-for-Sale
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Non-NEOs
Non-NEOs [Member]
Corporate notes
Corporate Debt Securities [Member]
Net increase (decrease) in cash, cash equivalents, and restricted cash
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Product [Member]