Document and Entity Information Research And Development Agreements Research and development agreements Revenue from Research And Development Agreements when the scientific or clinical results stipulated in the agreement have been met and there are no ongoing obligations on the part of the company Changes In Fair Value Of Warrants This item represents the change in fair value of warrants. (Increase) decrease in fair value of warrants Increase (decrease) in fair value of warrants Stock Issued During Period, Value, Common Stock for Cash Services and License Rights Equity impact of the value of common stock issued during the period. Includes shares issued for cash, services and license rights. Issuance of common stock for cash, services and license rights Stock Issued During Period, Shares, Common Stock for Cash Services and License Rights Issuance of common stock for cash, services and license rights (in shares) Number of shares issued during the period for cash, services and license rights. Stock Issued During Period, Value, SeriesAPreferredStock Issuance of Series A through Series E Preferred Stock for cash, net of issuance costs of $342 Equity impact of the value of Series A preferred stock issued through Series E preferred stock during the period. Issuance of Series A through Series E Preferred Stock for cash, net of issuance costs of $342 Stock Issued During Period, Shares, SeriesA Preferred Stock Issuance of Series A through Series E Preferred Stock for cash, net of issuance costs of $342 (in shares) Number of Series A preferred shares issued through Series E preferred stock issued during the period. Issuance of Series A through Series E Preferred Stock for cash, net of issuance costs of $342 (in shares) Stock Issued During Period, Value, Series E Preferred Stock Issuance of Series E Preferred Stock at $17.00 per Share Equity impact of the value of Series E preferred stock issued during the period. Issuance of Series E Preferred Stock at $17.00 per Share Stock Issued During Period, Shares, Series E Preferred Stock Issuance of Series E Preferred Stock at $17.00 per Share (in shares) Number of Series E preferred shares issued during the period. Issuance of Series E Preferred Stock at $17.00 per Share (in shares) Adjustments to Additional Paid in Capital, Payment Received Under Shareholder Note Receivable Principal payment received under shareholder note Receivable Adjustments to additional paid in capital resulting from the principal payment received under the shareholder note receivable. Amendment Description Stock Issued During Period, Value, Convertible Preferred Stock Convertible Preferred Stock Equity impact of the value of convertible preferred stock issued during the period. Amendment Flag Stock Issued During Period, Shares, Convertible Preferred Stock Convertible Preferred Stock (in shares) Number of convertible preferred shares issued during the period. Stock Issued During Period, Value, Common Stock Issuance of common stock, net of issuance costs of $1,944, $1,265 and $10,215 during the period ended December 31, 2010 and June 30, 2010 and 2009, respectively Equity impact of the value of common stock issued during the period. Stock Issued During Period, Shares, Common Stock Issuance of common stock, net of issuance costs of $1,944, $1,265 and $10,215 during the period ended December 31, 2010 and June 30, 2010 and 2009, respectively (in shares) Number of shares issued during the period. Series I Convertible Preferred Stock [Member] Series I Convertible Preferred Stock A Series I Convertible Preferred Stock that may be exchanged intocommon shares or other types of securities at the owner's option aslong as it is in accordance with the issuer's terms. Classifiedwithin stockholders' equity if nonredeemable or redeemable solelyat the option of the issuer. Classified within temporary equity ifredemption is outside the control of the issuer. Series III Convertible Preferred Stock [Member] Series III Convertible Preferred Stock A Series III Convertible Preferred Stock that may be exchanged intocommon shares or other types of securities at the owner's option aslong as it is in accordance with the issuer's terms. Classifiedwithin stockholders' equity if nonredeemable or redeemable solelyat the option of the issuer. Classified within temporary equity ifredemption is outside the control of the issuer. Adjustments to Additional Paid in Capital, Convertible Preferred Stock Issued Issuance Costs Convertible Preferred Stock, issuance costs Direct costs (e.g., legal and accounting fees) associated with issuing convertible preferred stock that is deducted from additional paid in capital. Also includes any direct costs associated with stock issues under a shelf registration. Adjustments to Additional Paid in Capital, Common Stock Issued Issuance Costs Common stock, issuance costs Direct costs (e.g., legal and accounting fees) associated with issuing common stock that is deducted from additional paid in capital. Adjustments to Additional Paid in Capital Convertible SeriesA Preferred Stock Issued Issuance Costs Series A Preferred Stock, issuance costs Direct costs (e.g., legal and accounting fees) associated with issuing Series A preferred stock that is deducted from additional paid in capital. Also includes any direct costs associated with stock issues under a shelf registration. Series E Preferred Stock, Par or Stated Value Per Share Series E Preferred Stock, par value (in dollars per share) Face amount or stated value per share of nonredeemable series E preferred stock (or preferred stock redeemable solely at the option of the issuer); generally not indicative of the fair market value per share. Start-up activities include those one-time activities related to opening a new facility, introducing a new product or service, conducting business in a new territory, conducting business with a new class of customer or beneficiary, initiating a new process in an existing facility, or commencing some new operation. Start-up activities include activities related to organizing a new entity (commonly referred to as organization costs) Organizational costs Organizational Costs Activity Selected Balance Sheet Information Stock Purchase Warrants The entire disclosure for warrants including description, amounts outstanding, fair value calculation and estimates. Warrants And rights Note Disclosure [Text Block] Basis of Presentation Basis of Presentation Current Fiscal Year End Date Document Period End Date Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Current Reporting Status Entity Filer Category Entity Public Float Entity Registrant Name Entity Central Index Key Entity Common Stock, Shares Outstanding Document Fiscal Year Focus Document Fiscal Period Focus Document Type Amortization of Financing Costs and Discounts Amortization of discounts and premiums on investments Issuance of Stock and Warrants for Services or Claims Stock issued pursuant to license agreement CONDENSED CONSOLIDATED BALANCE SHEETS Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Cash and cash equivalents at beginning of period Cash and cash equivalents at end of period Interest Paid Interest paid Increase (Decrease) in Accounts Payable and Accrued Liabilities Accounts payable and accrued expenses Increase (Decrease) in Employee Related Liabilities Accrued employee benefits Increase (Decrease) in Inventories Inventories Increase (Decrease) in Receivables Receivables Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Commitments, Contingencies and Debt Commitments and Contingencies Disclosure [Text Block] Common Stock, Shares Authorized Common Stock, shares authorized Common Stock, Shares, Issued Common Stock, shares issued Common Stock, Shares, Outstanding Common Stock, shares outstanding Common Stock, Value, Issued Common stock, no par value; shares authorized - 150,000; shares issued and outstanding - 38,635 and 38,756, respectively Cost of Goods Sold Cost of product sales and rentals Inventory Write-down Inventory write downs and reserves Liabilities, Current Total current liabilities Total current liabilities Current liabilities: Liabilities, Current [Abstract] Share-based Compensation Stock compensation expense Gain (Loss) on Sale of Property Plant Equipment Loss on property held for resale CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS Income Taxes Income Tax Disclosure [Text Block] Interest Expense Interest expense Inventory, Net Inventories Liabilities and Equity Total liabilities, convertible preferred stock and shareholders' deficit Total liabilities and shareholders' equity (deficit) LIABILITIES, CONVERTIBLE PREFERRED STOCK AND SHAREHOLDERS' DEFICIT Liabilities and Equity [Abstract] Long-term Debt, Current Maturities Current portion of long-term debt Long-term Debt, Excluding Current Maturities Long-term debt Net cash used for operating activities Net Cash Provided by (Used in) Operating Activities, Continuing Operations Operating activities: Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Proceeds from (Repayments of) Related Party Debt Payments received under shareholder notes Proceeds from (Repayments of) Restricted Cash, Financing Activities Restricted cash used as compensating balance Net loss attributable to common shareholders Net Income (Loss) Available to Common Stockholders, Basic Net loss and comprehensive loss Nonoperating Income (Expense) Total other income (expense) Operating Income (Loss) Loss from operations Loss from operations Revenues [Abstract] Revenues: Other Assets, Current Other current assets Proceeds from (Payments for) Other Financing Activities Other, net Other Nonoperating Income Other income Other Nonoperating Income (Expense) [Abstract] Other income (expense): Employee Savings Plan Pension and Other Postretirement Benefits Disclosure [Text Block] Preferred Stock, Par or Stated Value Per Share Convertible Preferred Stock, par value (in dollars per share) Proceeds from Issuance or Sale of Equity Net proceeds from issuance of common stock and warrants Proceeds from Issuance of Preferred Stock and Preference Stock Net proceeds from issuance of preferred stock Proceeds from Issuance of Warrants Payments received for stock purchase rights and other, net Proceeds from Issuance of Long-term Debt Proceeds from long-term debt Proceeds from Sale of Property, Plant, and Equipment Proceeds from sale of property held for resale Property, Plant and Equipment, Net Property and equipment, net Provision for Doubtful Accounts Provision for losses on accounts receivable Payments to Acquire Property, Plant, and Equipment Property and equipment purchases Payments to Acquire Short-term Investments Purchase of short-term investments Receivables, Net, Current Receivables Repayments of Long-term Debt Principal payments under long-term debt obligations Payments for Repurchase of Common Stock Repurchase of common stock Retained Earnings (Accumulated Deficit) Deficit accumulated during the development stage Revenue from Grants Grants Revenue, Net Total revenues Sales Revenue, Goods, Net Product sales and rentals Selling, General and Administrative Expense Selling, general and administrative Short-term Investments Short-term investments CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY (DEFICIT) AND COMPREHENSIVE LOSS Shareholders' deficit: Stockholders' Equity Attributable to Parent [Abstract] Series B Convertible Preferred Stock Stockholders' Equity Note Disclosure [Text Block] Series B Convertible Preferred Stock Supplemental Cash Flow Information [Abstract] Supplemental cash flow information Assets, Current Total current assets Total current assets Current assets: Assets, Current [Abstract] Warrants and Rights Outstanding Warrant liabilities Weighted Average Number of Shares Outstanding, Diluted Weighted average number of common shares outstanding (Diluted) (in shares) Weighted Average Number of Shares Outstanding, Basic Weighted average number of common shares outstanding (Basic) (in shares) Common Stock [Member] Common Stock Research and Development Expense Research and development Preferred Stock Preferred Stock [Member] Assets Total assets Total assets Investment Income, Interest Interest income Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Stock-Based Compensation Scenario, Unspecified [Domain] Statement [Table] Statement, Scenario [Axis] ASSETS Assets [Abstract] Statement Statement [Line Items] Capital Lease Obligations Incurred Equipment acquired under capital lease obligations Fair Value Disclosures [Text Block] Fair Value Measurements Quarterly Financial Information [Text Block] Quarterly Financial Data (Unaudited) Investing activities: Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Financing activities: Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Net cash used for investing activities Net Cash Provided by (Used in) Investing Activities, Continuing Operations Net cash provided by (used for) financing activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations Class of Stock [Domain] Stock Purchase Warrants Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity Stockholders' Equity, Period Increase (Decrease) Issuance of Stock Purchase Rights for cash in September 1995 and March 1996 Adjustments to Additional Paid in Capital, Warrant Issued Net Loss Per Common Share Class of Stock [Axis] Initial public offering of common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Stockholders' Equity Attributable to Parent Total shareholders' deficit BALANCE BALANCE Total shareholders' equity (deficit) Statement, Equity Components [Axis] Retained Earnings [Member] Deficit Accumulated During the Development Stage Equity Component [Domain] Initial public offering of common stock at $56.00 per share, net of issuance costs of $2,865 Stock Issued During Period, Value, New Issues Exercise of stock options and stock purchase warrants, and issuance of stock under Employee Stock Purchase Plan Stock Issued During Period, Value, Share-based Compensation, Net of Forfeitures Stock Issued During Period, Value, Employee Stock Purchase Plan Issuance of stock under Direct Stock Purchase Plan Issuance of restricted stock, net of cancellations Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures Conversion of preferred stock Stock Issued During Period, Value, Conversion of Convertible Securities Stock Issued During Period, Value, Stock Dividend Dividends and yields on preferred stock Stock Repurchased and Retired During Period, Value Repurchase and retirement of common shares outstanding Stock Issued During Period, Shares, New Issues Initial public offering of common stock at $56.00 per share, net of issuance costs of $2,865 (in shares) Stock Issued During Period, Shares, Share-based Compensation, Net of Forfeitures Exercise of stock options and stock purchase warrants, and issuance of stock under Employee Stock Purchase Plan (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of stock under Direct Stock Purchase Plan (in shares) Issuance of restricted stock, net of cancellations (in shares) Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures Stock Issued During Period, Shares, Conversion of Convertible Securities Conversion of preferred stock (in shares) Stock Repurchased and Retired During Period, Shares Repurchase and retirement of common shares outstanding (in shares) Stock Issued During Period, Shares, Period Increase (Decrease) Licenses, Royalties and Collaborative Agreements and Commitments Collaborative Arrangement Disclosure [Text Block] Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs Initial public offering of common stock, issuance costs Costs and Expenses [Abstract] Costs and expenses: Costs and Expenses Total costs and expenses Earnings Per Share [Text Block] Net Loss Per Common Share Depreciation, Depletion and Amortization Depreciation and amortization Stockholders' Equity, Including Portion Attributable to Noncontrolling Interest [Abstract] Shareholders' equity (deficit): Stockholders' Equity, Including Portion Attributable to Noncontrolling Interest Total shareholders' equity Commitments and Contingencies COMMITMENTS AND CONTINGENCIES (Notes 7 and 8) Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used for operating activities: Nature of Operations [Text Block] Organization and Summary of Significant Accounting Policies Accounts Payable and Accrued Liabilities, Current Accounts payable and accrued expenses Accrued Employee Benefits, Current Accrued employee benefits Compensation expense related to stock options and warrants granted Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Preferred Stock Dividends, Shares Dividends and yields on preferred stock (in shares) Net increase (decrease) in cash and cash equivalents Net Cash Provided by (Used in) Continuing Operations Organization and Summary of Significant Accounting Policies Organization, Consolidation, Basis of Presentation, Business Description and Accounting Policies [Text Block] Licenses, Royalties and Collaborative Agreements and Commitments Preferred Stock, Dividend Rate, Percentage Convertible Preferred Stock, rate of interest (in percentage) Shares, Outstanding BALANCE (in shares) BALANCE (in shares) Commitments, Contingencies and Debt Income Taxes Fair Value Measurements Subsequent Events Subsequent Events [Text Block] Employee Savings Plan Quarterly Financial Data (Unaudited) Stock-Based Compensation Basis of Accounting [Text Block] Basis of Presentation Proceeds from Sale, Maturity and Collection of Short-term Investments Maturities of short-term investments Organization and Summary of Significant Accounting Policies Subsequent Events Selected Balance Sheet Information Supplemental Balance Sheet Disclosures [Text Block] Increase (Decrease) in Other Current Assets Other current assets Earnings Per Share, Basic and Diluted Net loss per share attributable to common shareholders (Basic and Diluted) (in dollars per share) Series B1 Non voting Converible Preferred Stock [Member] Series B-1 non-voting convertible preferred stock A preferred stock which is not entitled to vote on matters on which common shares are generally entitled to vote that may be exchanged into common shares or other types of securities at the owner's option as long as it is in accordance with the issuer's terms. Classified within stockholders' equity if nonredeemable or redeemable solely at the option of the issuer. Classified within temporary equity if redemption is outside the control of the issuer. Liabilities Total liabilities Temporary Equity, Carrying Amount Series B-1 non-voting convertible preferred stock, no par value; shares authorized and reserved - zero and 39, respectively; shares issued and outstanding - zero and 12, respectively Temporary Equity, Shares Authorized Preferred stock, shares authorized Temporary Equity, Shares Issued Preferred stock, shares issued Temporary Equity, Shares Outstanding Preferred stock, shares outstanding Net Income (Loss) Attributable to Parent Net loss Net loss Temporary Equity, Accretion of Dividends Accretion of convertible preferred stock Preferred stock, shares reserved Temporary Equity Shares Reserved For Future Issuance Aggregate number of securities classified as temporary equity reserved for future issuance.