0000001 - Document - Cover link:presentationLink link:calculationLink link:definitionLink 0000002 - Document - Audit Information link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - CONSOLIDATED BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS) link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 9952157 - Disclosure - Organization link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Revenue link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Selected Balance Sheet Components link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Investments link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Stock-Based Compensation link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Revolving Credit Agreement link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Net Income (Loss) Per Common Share link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Employee Benefit Plans link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Nexobrid License and Supply Agreements link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952171 - Disclosure - Segment Information link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Revenue (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Selected Balance Sheet Components (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - 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Disclosure - Revenue - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Revenue - Schedule of disaggregation of revenue (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Revenue - Schedules of concentration of credit risk (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Selected Balance Sheet Components - Schedule of inventory (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Selected Balance Sheet Components - Schedule of property and equipment, net (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Selected Balance Sheet Components - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Selected Balance Sheet Components -Schedule of finite-lived intangible assets (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Selected Balance Sheet Components - Intangible assets (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Selected Balance Sheet Components - Schedule of accrued expenses (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Leases - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Leases - Assets And Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Leases - Maturities of Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Leases - Maturities of Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Leases - Maturities of Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Leases - Lease Term and Discount Rate (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Investments - Schedule of Fair Value of Securities, Not Including Cash (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Investments - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Stock-Based Compensation - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Stock-Based Compensation - Schedule of non-cash stock-based compensation expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Stock-Based Compensation - Schedule of fair value assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Stock-Based Compensation - Schedule of activity for service-based stock options (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Stock-Based Compensation - Schedule of restricted stock awards activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - 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Deferred Tax Assets (Liabilities) (Details) link:presentationLink link:calculationLink link:definitionLink 9955552 - Disclosure - Income Taxes - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955553 - Disclosure - Employee Benefit Plans (Details) link:presentationLink link:calculationLink link:definitionLink 9955554 - Disclosure - NexoBrid License and Supply Agreements (Details) link:presentationLink link:calculationLink link:definitionLink 9955555 - Disclosure - Commitments and Contingencies - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955556 - Disclosure - Commitments and Contingencies - Future Minimum Payments (Details) link:presentationLink link:calculationLink link:definitionLink 9955556 - Disclosure - Commitments and Contingencies - Future Minimum Payments (Details) link:presentationLink link:calculationLink link:definitionLink 9955557 - Disclosure - Segment Information (Details) link:presentationLink link:calculationLink link:definitionLink