Share-based Payment Arrangement [Abstract] Schedule of non-cash stock-based compensation expense Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Schedule of weighted average assumptions used to estimate fair value of each service-based stock option grant Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Leases [Abstract] Leases Lessee, Operating Leases [Text Block] Leases Lessee, Finance Leases [Text Block] Related Party Transactions [Abstract] Nexobrid License Agreement License Agreement [Text Block] License Agreement [Text Block] Operating leases Leases, Operating [Abstract] Total Operating Leases, Future Minimum Payments Due 2019 Operating Leases, Future Minimum Payments Due, Next Twelve Months 2020 Operating Leases, Future Minimum Payments, Due in Two Years 2021 Operating Leases, Future Minimum Payments, Due in Three Years 2022 Operating Leases, Future Minimum Payments, Due in Four Years 2023 Operating Leases, Future Minimum Payments, Due in Five Years More than 5 years Operating Leases, Future Minimum Payments, Due Thereafter Capital leases Leases, Capital [Abstract] Total Capital Leases, Future Minimum Payments Due 2019 Capital Leases, Future Minimum Payments Due, Next Twelve Months 2020 Capital Leases, Future Minimum Payments Due in Two Years 2021 Capital Leases, Future Minimum Payments Due in Three Years 2022 Capital Leases, Future Minimum Payments Due in Four Years 2023 Capital Leases, Future Minimum Payments Due in Five Years More than 5 years Capital Leases, Future Minimum Payments Due Thereafter Operating And Capital Leases [Abstract] Operating And Capital Leases [Abstract] Operating And Capital Leases [Abstract] Total Operating and Capital Leases and Purchase Commitments, Future Minimum Payments Due Operating and Capital Leases and Purchase Commitments, Future Minimum Payments Due 2019 Operating and Capital Leases and Purchase Commitments, Future Minimum Payments Due, Current Operating and Capital Leases and Purchase Commitments, Future Minimum Payments Due, Current 2020 Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due In Two Years Operating and Capital Leases and Purchase Commitments, Due In Two Years 2021 Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due In Three Years Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due In Three Years 2022 Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due In Four Years Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due In Four Years 2023 Operating and Capital Leases and Purchase Commitments, Future Minimum Payments Due in Five Years Operating and Capital Leases and Purchase Commitments, Future Minimum Payments Due in Five Years More than 5 years Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due Thereafter Operating and Capital Leases and Purchase Commitments, Future Minimum Payments, Due Thereafter Operating Leases Lessee, Operating Lease, Liability, Payment, Due [Abstract] 2019 Lessee, Operating Lease, Liability, Payments, Remainder of Fiscal Year 2020 Lessee, Operating Lease, Liability, Payments, Due Year Two 2021 Lessee, Operating Lease, Liability, Payments, Due Year Three 2022 Lessee, Operating Lease, Liability, Payments, Due Year Four 2023 Lessee, Operating Lease, Liability, Payments, Due Year Five 2024 Lessee, Operating Lease, Liability, Payments, Due Year Six Lessee, Operating Lease, Liability, Payments, Due Year Six Thereafter Lessee, Operating Lease, Liability, Payments, Due after Year Six Lessee, Operating Lease, Liability, Payments, Due after Year Six Total lease payments Lessee, Operating Lease, Liability, Payments, Due Less: Interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount Present value of lease liabilities Operating Lease, Liability Finance Leases Finance Lease, Liability, Payment, Due [Abstract] 2019 Finance Lease, Liability, Payments, Remainder of Fiscal Year 2020 Finance Lease, Liability, Payments, Due Year Two 2021 Finance Lease, Liability, Payments, Due Year Three 2022 Finance Lease, Liability, Payments, Due Year Four 2023 Finance Lease, Liability, Payments, Due Year Five 2024 Finance Lease, Liability, Payments Due Year Six Finance Lease, Liability, Payments Due Year Six Thereafter Finance Lease, Liability, Payments, Due after Year Six Finance Lease, Liability, Payments, Due after Year Six Total lease payments Finance Lease, Liability, Payment, Due Less: Interest Finance Lease, Liability, Undiscounted Excess Amount Present value of lease liabilities Finance Lease, Liability 2019 Lease Liability Payments Due Remainder Of Fiscal Year Lease Liability Payments Due Remainder Of Fiscal Year 2020 Lease Liability Payments Due Year Two Lease Liability Payments Due Year Two 2021 Lease Liability Payments Due Year Three Lease Liability Payments Due Year Three 2022 Lease Liability Payments Due Year Four Lease Liability Payments Due Year Four 2023 Lease Liability Payments Due Year Five Lease Liability Payments Due Year Five 2024 Lease Liability Payments Due Year Six Lease Liability Payments Due Year Six Thereafter Lease Liability Payments Due After Year Six Lease Liability Payments Due After Year Six Total lease payments Lease Liability Payments Due Lease Liability Payments Due Less: Interest Lease, Liability, Undiscounted Excess Amount Lease, Liability, Undiscounted Excess Amount Present value of lease liabilities Lease Liability Lease Liability Assets And Liabilities Assets And Liabilities, Leases [Table Text Block] Assets And Liabilities, Leases [Table Text Block] Maturity of lease liabilities Finance Lease, Liability, Maturity [Table Text Block] Maturity of lease liabilities Lessee, Operating Lease, Liability, Maturity [Table Text Block] Lease term and discount rate Lease, Cost [Table Text Block] Schedule Of Future Minimum Rental Payments For Operating And Capital Leases Schedule Of Future Minimum Rental Payments For Operating And Capital Leases Table Text Block Tabular disclosure of operating and capital leases. Organization, Consolidation and Presentation of Financial Statements [Abstract] Number of reportable segments Number of Reportable Segments Accumulated deficit Retained Earnings (Accumulated Deficit) Net income (loss) Net Income (Loss) Attributable to Parent Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Short-term investments Short-term Investments Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table] Income Statement Location [Axis] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] Cost of goods sold Cost of Sales [Member] Research and development Research and Development Expense [Member] Selling, general and administrative Selling, General and Administrative Expenses [Member] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Non-cash stock-based compensation expense Share-based Payment Arrangement, Expense Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Subsequent Event Type [Axis] Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event Type [Domain] Subsequent Event Subsequent Event [Member] Award Type [Axis] Award Type [Axis] Award Type [Domain] Award Type [Domain] Service-Based Stock Options Share-based Payment Arrangement, Option [Member] Director options Director [Member] Employee Stock Employee Stock [Member] Restricted Stock Units (RSUs) Restricted Stock Units (RSUs) [Member] Statistical Measurement [Axis] Statistical Measurement [Axis] Statistical Measurement [Domain] Statistical Measurement [Domain] Maximum Maximum [Member] Minimum Minimum [Member] Plan Name [Axis] Plan Name [Axis] Plan Name [Domain] Plan Name [Domain] 2004, 2001, 1992, and 2009 Plans Prior Plans [Member] Represents the information pertaining to the Prior Plans consisting of 1992 Stock Option Plan, the 2001 Stock Option Plan and the Amended and Restated 2004 Equity Incentive Plan. 2017 Plan Omnibus Incentive Plan 2017 [Member] Omnibus Incentive Plan 2017 [Member] Stock-Based Compensation Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Expiration period Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period Number of shares available for grant (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant Employee Stock Purchase Plan, number of shares authorized (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized Employee Stock Purchase Plan, grants since inception (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Non-Option Equity Instruments, Granted Shares issued under the Employee Stock Purchase Plan ( in shares ) Stock Issued During Period, Shares, Employee Stock Purchase Plans Shares issued under the Employee Stock Purchase Plan Stock Issued During Period, Value, Employee Stock Purchase Plan Granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Vesting period Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period Grant date fair value (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Restricted stock units, grant-date fair value Restricted Stock or Unit Expense Warrants and Rights Note Disclosure [Abstract] Stock Purchase Warrants Warrants and Rights Note Disclosure [Text Block] The entire disclosure for warrants including description, amounts outstanding, fair value calculation and estimates. Balance Sheet Related Disclosures [Abstract] Accounts payable and accrued expenses: Accounts Payable and Accrued Liabilities, Current [Abstract] Bonus related compensation Accrued Bonuses Employee related accruals Employee-related Liabilities, Current Other accrued expenses Other Accrued Liabilities, Current Total Accounts Payable and Accrued Liabilities, Current Revenue from Contract with Customer [Abstract] Disaggregation of Revenue [Table] Disaggregation of Revenue [Table] Product and Service [Axis] Product and Service [Axis] Product and Service [Domain] Product and Service [Domain] Implants Implants [Member] Implants [Member] Biopsy kits Biopsy Kits [Member] Biopsy Kits [Member] Epicel Epicel [Member] Epicel [Member] Contract with Customer, Basis of Pricing [Axis] Contract with Customer, Basis of Pricing [Axis] Contract with Customer, Basis of Pricing [Domain] Contract with Customer, Basis of Pricing [Domain] Contracted rate Fixed-price Contract [Member] Time-and-materials Contract Time-and-materials Contract [Member] Contract with Customer, Sales Channel [Axis] Contract with Customer, Sales Channel [Axis] Contract with Customer, Sales Channel [Domain] Contract with Customer, Sales Channel [Domain] Third party distributor Sales Channel, Through Intermediary [Member] Provider or Facility Provider or Facility [Member] Provider or Facility [Member] Direct bill Sales Channel, Directly to Consumer [Member] Adjustments for New Accounting Pronouncements [Axis] Adjustments for New Accounting Pronouncements [Axis] Type of Adoption [Domain] Type of Adoption [Domain] Accounting Standards Update 2014-09 Accounting Standards Update 2014-09 [Member] Initial Application Period Cumulative Effect Transition [Axis] Initial Application Period Cumulative Effect Transition [Axis] Initial Application Period Cumulative Effect Transition [Domain] Initial Application Period Cumulative Effect Transition [Domain] Difference between Revenue Guidance in Effect before and after Topic 606 Difference between Revenue Guidance in Effect before and after Topic 606 [Member] Disaggregation of Revenue [Line Items] Disaggregation of Revenue [Line Items] Product sales, net Revenue from Contract with Customer, Excluding Assessed Tax Basis of Presentation [Abstract] Basis of Presentation [Abstract] Basis of Presentation Basis of Accounting [Text Block] Stock-based Compensation Share-based Payment Arrangement [Text Block] Accounting Policies [Abstract] Recent Accounting Pronouncements Significant Accounting Policies [Text Block] Statement of Cash Flows [Abstract] Operating activities: Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Net loss Adjustments to reconcile net loss to net cash used for operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Depreciation and amortization expense Depreciation, Depletion and Amortization Stock compensation expense Share-based Payment Arrangement, Noncash Expense Change in fair value of warrants Fair Value Adjustment of Warrants Loss on sale of fixed assets Gain (Loss) on Disposition of Assets Foreign currency translation loss Foreign Currency Transaction Gain (Loss), before Tax Amortization of premiums and discounts on marketable securities Accretion (Amortization) of Discounts and Premiums, Investments Non-cash lease cost Finance Lease, Right-of-Use Asset, Amortization Change in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] Inventory Increase (Decrease) in Inventories Accounts receivable Increase (Decrease) in Receivables Prepaid and other current assets Increase (Decrease) in Other Current Assets Accounts payable Increase (Decrease) in Accounts Payable and Accrued Liabilities Accrued expenses Increase (Decrease) in Employee Related Liabilities Operating lease liabilities Increase (Decrease) In Lease Liabilities Increase (Decrease) In Lease Liabilities Other assets and liabilities, net Increase (Decrease) in Other Operating Assets and Liabilities, Net Net cash used in operating activities Net Cash Provided by (Used in) Operating Activities Investing activities: Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Purchases of short-term investments Payments to Acquire Businesses, Net of Cash Acquired Maturities of short-term investments Proceeds from Sale, Maturity and Collection of Short-term Investments Expenditures for property, plant and equipment Payments to Acquire Property, Plant, and Equipment Net cash provided by (used in) investing activities Net Cash Provided by (Used in) Investing Activities Financing activities: Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Net proceeds from equity offering Proceeds from Issuance of Preferred Stock and Preference Stock Net proceeds from common stock issuance due to stock option exercises Proceeds from Stock Options Exercised Proceeds from exercise of warrants Proceeds from Warrant Exercises Other Proceeds from (Payments for) Other Financing Activities Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities Net increase in cash and cash equivalents Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Cash and cash equivalents at beginning of period Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents Cash and cash equivalents at end of period Investments, Debt and Equity Securities [Abstract] Cash Equivalents and Investments Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Income Statement [Abstract] Statement [Table] Statement [Table] Product Product [Member] Statement Statement [Line Items] Cost of product sales Cost of Goods and Services Sold Gross profit Gross Profit Research and development Research and Development Expense Selling, general and administrative Selling, General and Administrative Expense Total operating expenses Operating Expenses Income (loss) from operations Operating Income (Loss) Other income (expense): Other Nonoperating Income (Expense) [Abstract] Increase (decrease) in fair value of warrants Interest income Investment Income, Interest Interest expense Interest Expense Other income (expense) Other Nonoperating Income (Expense) Total other income (expense) Nonoperating Income (Expense) Net income (loss) Earnings Per Share, Basic (in dollars per share) Earnings Per Share, Basic Weighted Average Number of Shares Outstanding, Basic (in shares) Weighted Average Number of Shares Outstanding, Basic Earnings Per Share, Diluted (in dollars per share) Earnings Per Share, Diluted Weighted Average Number of Shares Outstanding, Diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Statement of Financial Position [Abstract] Allowance for doubtful accounts Accounts Receivable, Allowance for Credit Loss Common stock, authorized (in shares) Common Stock, Shares Authorized Common stock, issued (in shares) Common Stock, Shares, Issued Common stock, outstanding (in shares) Common Stock, Shares, Outstanding Earnings Per Share [Abstract] Schedule of net loss attributable to common shareholders and share data used in the basic and diluted earnings per share computations using the two class method Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Debt Securities, Available-for-sale [Table] Debt Securities, Available-for-sale [Table] Financial Instrument [Axis] Financial Instrument [Axis] Financial Instruments [Domain] Financial Instruments [Domain] Repurchase agreements Repurchase Agreements [Member] Debt Securities, Available-for-sale [Line Items] Debt Securities, Available-for-sale [Line Items] Payments to acquire investment funds and securities Payments to Acquire Debt Securities, Available-for-sale Class of Warrant or Right [Table] Class of Warrant or Right [Table] Equity Components [Axis] Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Warrants Amounts Warrant [Member] Measurement Input Type [Axis] Measurement Input Type [Axis] Measurement Input Type [Domain] Measurement Input Type [Domain] Expected rate Measurement Input, Expected Dividend Rate [Member] Stock Purchase Warrants Class of Warrant or Right [Line Items] Measurement input Warrants and Rights Outstanding, Measurement Input Shares issued Shares, Issued Exercise price Investment Warrants, Exercise Price Fair Value Disclosures [Abstract] Fair Value, Recurring and Nonrecurring [Table] Fair Value, Recurring and Nonrecurring [Table] Money market funds Money Market Funds [Member] Commercial paper Commercial Paper [Member] Corporate notes Corporate Debt Securities [Member] U.S. government securities US Government Agencies Debt Securities [Member] U.S. asset-backed securities Asset-backed Securities [Member] Measurement Frequency [Axis] Measurement Frequency [Axis] Measurement Frequency [Domain] Measurement Frequency [Domain] Recurring Fair Value, Recurring [Member] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV [Domain] Level 1 Fair Value, Inputs, Level 1 [Member] Level 2 Fair Value, Inputs, Level 2 [Member] Level 3 Fair Value, Inputs, Level 3 [Member] Assets and liabilities that are measured at fair value on a recurring basis Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Assets: Assets, Fair Value Disclosure [Abstract] Assets, fair value Assets, Fair Value Disclosure Balance Sheet Location [Axis] Balance Sheet Location [Axis] Balance Sheet Location [Domain] Balance Sheet Location [Domain] Cash equivalents Cash Equivalents [Member] Short-term investments Short-term Investments [Member] Amortized Cost Debt Securities, Available-for-sale, Amortized Cost Gains Debt Securities, Available-for-sale, Accumulated Gross Unrealized Gain, before Tax Losses Debt Securities, Available-for-sale, Accumulated Gross Unrealized Loss, before Tax Fair Value Debt Securities, Available-for-sale Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Property, Plant and Equipment, Type [Axis] Property, Plant and Equipment, Type [Axis] Property, Plant and Equipment, Type [Domain] Property, Plant and Equipment, Type [Domain] Machinery and equipment Machinery and Equipment [Member] Furniture, fixtures and office equipment Furniture and Fixtures [Member] Computer equipment and software Computer Equipment [Member] Leasehold improvements Leasehold Improvements [Member] Construction in process Construction in Progress [Member] Property and equipment, net: Property, Plant and Equipment [Line Items] Total property and equipment, gross Property, Plant and Equipment, Gross Financing right-of-use lease Finance Lease, Right-of-Use Asset Less: Accumulated depreciation Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Total, net Property, Plant and Equipment, Net Depreciation and amortization Depreciation, Depletion and Amortization, Excluding Intangible Assets Depreciation, Depletion and Amortization, Excluding Intangible Assets Cover page. Document Type Document Type Document Quarterly Report Document Quarterly Report Document Period End Date Document Period End Date Document Transition Report Document Transition Report Entity File Number Entity File Number Entity Registrant Name Entity Registrant Name Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Tax Identification Number Entity Address, Address Line One Entity Address, Address Line One Entity Address, City or Town Entity Address, City or Town Entity Address, State or Province Entity Address, State or Province Entity Address, Postal Zip Code Entity Address, Postal Zip Code City Area Code City Area Code Local Phone Number Local Phone Number Title of 12(b) Security Title of 12(b) Security Trading Symbol Trading Symbol Security Exchange Name Security Exchange Name Entity Current Reporting Status Entity Current Reporting Status Entity Interactive Data Current Entity Interactive Data Current Entity Filer Category Entity Filer Category Entity Small Business Entity Small Business Entity Emerging Growth Company Entity Emerging Growth Company Entity Shell Company Entity Shell Company Entity Common Stock, Shares Outstanding (in shares) Entity Common Stock, Shares Outstanding Entity Central Index Key Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Amendment Flag Amendment Flag Schedule of fair value of securities, not including cash Debt Securities, Available-for-sale [Table Text Block] Operating Lease Term (in years) Operating Lease, Weighted Average Remaining Lease Term Finance Lease Term (in years) Finance Lease, Weighted Average Remaining Lease Term Operating Lease Discount Rate ( as a percent ) Operating Lease, Weighted Average Discount Rate, Percent Finance Lease Discount Rate ( as a percent ) Finance Lease, Weighted Average Discount Rate, Percent Allowance for doubtful accounts Allowance for Doubtful Other Receivables, Current Prior period sales Prior period sales Prior period sales Net Earnings (Loss) Per Common Share Earnings Per Share [Text Block] Selected Balance Sheet Components Supplemental Balance Sheet Disclosures [Text Block] Schedule of Related Party Transactions, by Related Party [Table] Schedule of Related Party Transactions, by Related Party [Table] Counterparty Name [Axis] Counterparty Name [Axis] Counterparty Name [Domain] Counterparty Name [Domain] MediWound Ltd MediWound Ltd [Member] MediWound Ltd [Member] Related Party Transaction [Line Items] Related Party Transaction [Line Items] Payable License Agreement, Payable License Agreement, Payable Contingent Consideration License Agreement, Contingent Consideration License Agreement, Contingent Consideration Max contingent consideration License Agreement, Contingent Consideration, Maximum License Agreement, Contingent Consideration, Maximum Sales Initial Milestone License Agreement, Initial Milestone, Sales License Agreement, Initial Milestone, Sales ASSETS Assets [Abstract] Right-of-use assets Operating Lease, Right-of-Use Asset Finance Right Of Use Asset Right Of Use Asset Right Of Use Asset Liabilities Liabilities [Abstract] Current liabilities: Liabilities, Current [Abstract] Operating Operating Lease, Liability, Current Finance Finance Lease, Liability, Current Lease Liability Current Lease Liability Current Lease Liability Current Non-current Liabilities, Noncurrent [Abstract] Operating Operating Lease, Liability, Noncurrent Finance Finance Lease, Liability, Noncurrent Lease Liability Noncurrent Lease Liability Noncurrent Lease Liability Noncurrent Expected dividend rate Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected stock price volatility Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate Risk-free interest rate Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Expected life Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Short-term lease cost Short-term Lease, Cost Net Lease Assets Lease Liability Operating Lease Expense Operating Lease, Expense Finance lease expense Finance Lease, Interest Expense Measurement of Lease Liability Measurement Of Lease Liability Measurement Of Lease Liability Schedule of inventory Schedule of Inventory, Current [Table Text Block] Schedule of property and equipment, net Property, Plant and Equipment [Table Text Block] Schedule of accounts payable and accrued expenses Schedule of Accounts Payable and Accrued Liabilities [Table Text Block] Accounting for Leases Lessee, Leases [Policy Text Block] Measuring Credit Losses on Financial Instruments Credit Loss, Financial Instrument [Policy Text Block] Warrants exercised for common stock Warrants Exercised For Common Stock Warrants Exercised For Common Stock Interest paid (net of interest capitalized) Interest Paid, Excluding Capitalized Interest, Operating Activities Additions to equipment in process included in accounts payable Capital Expenditures Incurred but Not yet Paid Right-of-use asset and lease liability recognized Right-of-Use Asset Obtained in Exchange for Finance Lease Liability Fair Value Measurements Fair Value Disclosures [Text Block] Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Schedule of revenue by product and customer Disaggregation of Revenue [Table Text Block] Schedules of concentration of risk Schedules of Concentration of Risk, by Risk Factor [Table Text Block] Incentive from Lessor Tenant Improvements, Contributed by Landlord Tenant Improvements, Contributed by Landlord Deferred rent asset Deferred Rent Asset, Net, Current Statement of Stockholders' Equity [Abstract] Common Stock Common Stock [Member] Accumulated Other Comprehensive Income (Loss) AOCI Attributable to Parent [Member] Accumulated Deficit Retained Earnings [Member] Increase (Decrease) in Shareholders' Equity Increase (Decrease) in Stockholders' Equity [Roll Forward] Beginning balance (in shares) Shares, Outstanding Beginning balance Stockholders' Equity Attributable to Parent Compensation expense related to stock options granted, net of forfeitures APIC, Share-based Payment Arrangement, Increase for Cost Recognition Issuance of common stock, net of issuance costs (in shares) Stock Issued During Period, Shares, New Issues Issuance of common stock, net of issuance costs Stock Issued During Period, Value, New Issues Stock option exercises (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Stock option exercises Stock Issued During Period, Value, Stock Options Exercised Change in unrealized gain (loss) on investments Unrealized Gain (Loss) on Securities Exercise of warrants resulting in the issuance of common stock (in shares) Stock Issued During Period, Shares, Exercise Of Warrants Stock Issued During Period, Shares, Exercise Of Warrants Exercise of warrants resulting in issuance of common stock Stock Issued During Period, Value, Exercise Of Warrants Stock Issued During Period, Value, Exercise Of Warrants Net change in warrant valuation of exercised warrants Warrant, Down Round Feature, (Increase) Decrease in Equity, Amount Ending balance (in shares) Ending balance Current assets: Assets, Current [Abstract] Accounts receivable (net of allowance for doubtful accounts of $643 and $514, respectively) Accounts Receivable, after Allowance for Credit Loss, Current Inventory Inventory, Net Other current assets Other Assets, Current Total current assets Assets, Current Property and equipment, net Total assets Assets LIABILITIES AND SHAREHOLDERS’ EQUITY Liabilities and Equity [Abstract] Accounts payable Accounts Payable, Current Accrued expenses Current portion of operating lease liabilities Other liabilities Other Liabilities, Current Total current liabilities Liabilities, Current Operating lease liabilities Other long-term liabilities Deferred Costs, Leasing, Net, Noncurrent Total liabilities Liabilities COMMITMENTS AND CONTINGENCIES Commitments and Contingencies Shareholders’ equity: Stockholders' Equity Attributable to Parent [Abstract] Common stock, no par value; shares authorized — 75,000; shares issued and outstanding — 44,520 and 43,578, respectively Common Stock, Value, Issued Other comprehensive gain (loss) Accumulated Other Comprehensive Income (Loss), Net of Tax Warrants Warrants and Rights Outstanding Accumulated deficit Total shareholders’ equity Total liabilities and shareholders’ equity Liabilities and Equity Schedule of Stock by Class [Table] Schedule of Stock by Class [Table] Class of Stock [Axis] Class of Stock [Axis] Class of Stock [Domain] Class of Stock [Domain] Options Options Held [Member] Restricted Stock Restricted Stock [Member] Class of Stock [Line Items] Class of Stock [Line Items] Numerator: Net Income (Loss) Attributable to Parent [Abstract] Denominator: Weighted Average Number of Shares Outstanding, Diluted [Abstract] Aggregate number of common equivalent shares (related to options, warrants and preferred stock) excluded from diluted net loss per common share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Summary of valuation of the Company's investments and financial instruments that are measured at fair value on a recurring basis Fair Value, Liabilities Measured on Recurring Basis [Table Text Block] Revenue Revenue from Contract with Customer [Text Block] Inventory: Inventory, Net [Abstract] Raw materials Inventory, Raw Materials, Gross Work-in-process Inventory, Work in Process, Gross Finished goods Inventory, Finished Goods, Gross Inventory Organization Nature of Operations [Text Block] Schedule of cash flow, supplemental disclosures Schedule of Cash Flow, Supplemental Disclosures [Table Text Block] Concentration Risk [Table] Concentration Risk [Table] Concentration Risk Type [Axis] Concentration Risk Type [Axis] Concentration Risk Type [Domain] Concentration Risk Type [Domain] Customer concentration Customer Concentration Risk [Member] Customer [Axis] Customer [Axis] Customer [Domain] Customer [Domain] MACI Carticel And MACI Distributor [Member] Carticel And MACI Distributor [Member] Epicel customer 1 [Member] customer 1 [Member] Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Domain] Concentration Risk Benchmark [Domain] Revenue Concentration Revenue Benchmark [Member] Accounts Receivable Concentration Accounts Receivable [Member] CONCENTRATION Concentration Risk [Line Items] Concentration risk Concentration Risk, Percentage Statement of Comprehensive Income [Abstract] Other comprehensive income (loss): Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Unrealized (loss) gain on investments Other Comprehensive Income (Loss), Available-for-sale Securities Adjustment, Net of Tax, Portion Attributable to Parent Comprehensive income (loss) Comprehensive Income (Loss), Net of Tax, Attributable to Parent