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Instruments [Table] Schedule of Long-Term Debt Instruments [Table] Total unrecognized compensation cost Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Shares issued under the Employee Stock Purchase Plan Stock Issued During Period, Value, Employee Stock Purchase Plan Accounting Policies [Abstract] Accounting Policies [Abstract] Sale of Stock [Domain] Sale of Stock [Domain] Risk-free interest rate, maximum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Expected stock price volatility, maximum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum Total net deferred tax assets Deferred Tax Assets, Net Intrinsic value of stock options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Finance Lease, Liability, Current, Statement of Financial Position [Extensible List] Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration] Entity Address, City or Town Entity Address, City or Town Supply agreement, term Purchase Obligation, Supply Agreement, Term Purchase Obligation, Supply Agreement, Term 2025 Purchase Obligation, to be Paid, Year Two Duration of lease renewal terms Lessee, Lease, Renewal Term Lessee, Lease, Renewal Term Principles of Consolidation Consolidation, Policy [Policy Text Block] Research and orphan drug credits Effective Income Tax Rate Reconciliation, Tax Credit, Amount 2026 Purchase Obligation, to be Paid, Year Three Selected Balance Sheet Components Supplemental Balance Sheet Disclosures [Text Block] Investing activities: Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Change in Accounting Estimate, Type [Domain] Change in Accounting Estimate, Type [Domain] Document Transition Report Document Transition Report Through Intermediary Sales Channel, Through Intermediary [Member] Financial Instruments Fair Value of Financial Instruments, Policy [Policy Text Block] Accounts payable Increase (Decrease) in Accounts Payable Common stock, shares authorized (in shares) Common Stock, Shares Authorized Estimated Fair Value Debt securities, fair value Debt Securities, Available-for-Sale Raw materials Inventory, Raw Materials, Gross Entity Public Float Entity Public Float Liabilities that are measured at fair value on a recurring basis Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Short-term investments Short-Term Investments [Member] Change in estimate of uncollectible (percent) Revenue, Revenue Recognized, Change in Uncollectible Analysis, Percentage Revenue, Revenue Recognized, Change in Uncollectible Analysis, Percentage Increase (decrease) in valuation allowance Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount Adjustments to reconcile net loss to net cash flows from operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Related Party Transactions [Abstract] Related Party Transactions [Abstract] Aggregate Intrinsic Value Share Based Compensation Arrangement By Share Based Payment Award Options Aggregate Intrinsic Value [Abstract] Share Based Compensation Arrangement By Share Based Payment Award Options Aggregate Intrinsic Value [Abstract] Less accumulated depreciation Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, Accumulated Depreciation and Amortization Restricted stock held for employee tax remittance included in accounts payable Restricted Stock Held For Employee Tax Remittance Included In Accounts Payable Restricted Stock Held For Employee Tax Remittance Included In Accounts Payable Restricted Cash Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Less: tenant improvement allowances Lessee, Operating Lease, Liability, Tenant Improvement Allowance Lessee, Operating Lease, Liability, Tenant Improvement Allowance Fair value of vested awards Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value Escrow deposit amount Escrow Deposit Other comprehensive income (loss): Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Forfeited (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Right-of-use assets Deferred Tax Liabilities, Leasing Arrangements 2025 Lease Liability Payments Due Year Two Lease Liability Payments Due Year Two Net proceeds from common stock issuance Proceeds from Stock Options Exercised Statement of Comprehensive Income [Abstract] Statement of Comprehensive Income [Abstract] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Contractual Obligation, Fiscal Year Maturity [Abstract] Contractual Obligation, Fiscal Year Maturity [Abstract] Income Taxes Income Tax, Policy [Policy Text Block] Document Financial Statement Error Correction Document Financial Statement Error Correction [Flag] Thereafter Lease, Liability, to be Paid After Year Five Lease, Liability, to be Paid After Year Five 2026 Finite-Lived Intangible Asset, Expected Amortization, Year Three Work-in-process Inventory, Work in Process, Gross Forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Revenue, Product and Service [Extensible List] Revenue, Product and Service [Extensible Enumeration] Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Sale of stock authorized value Sale of Stock, Authorized Value Sale of Stock, Authorized Value Entity Registrant Name Entity Registrant Name Effect of dilutive stock options and restricted stock units (in shares) Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements 2025 Finite-Lived Intangible Asset, Expected Amortization, Year Two More than 5 Years Contractual Obligation, to be Paid, after Year Five Cost of product sales Cost of Sales [Member] Documents Incorporated by Reference Documents Incorporated by Reference [Text Block] Auditor Name Auditor Name Document Period End Date Document Period End Date Ann Arbor, Michigan Ann Arbor, Michigan [Member] Ann Arbor, Michigan Exercisable at the end of the period (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price More than 5 Years Purchase Obligation, to be Paid, after Year Five Weighted-average discount rate - Finance lease discount rate Finance Lease, Weighted Average Discount Rate, Percent Other revenue Revenue Not from Contract with Customer, Other Entity Central Index Key Entity Central Index Key Revenue Concentration Risk Disclosure [Text Block] Total non-cash stock-based compensation expense Share-Based Payment Arrangement, Expense Intangible assets Cost Finite-Lived Intangible Assets, Gross Income tax expense (benefit) Reported income taxes Income Tax Expense (Benefit) Income Tax Authority [Domain] Income Tax Authority [Domain] Biopsy kits - direct bill Biopsy Kits [Member] Biopsy Kits [Member] Finance Finance Lease, Right-of-Use Asset, after Accumulated Amortization Employee related accruals Employee-related Liabilities, Current Fair Value Measurements Fair Value Disclosures [Text Block] Revenue Concentration Revenue Benchmark [Member] Award Date [Axis] Award Date [Axis] Disaggregation of Revenue Disaggregation of Revenue [Table Text Block] 2027 Contractual Obligation, to be Paid, Year Four Weighted-average remaining lease term - Operating lease term Operating Lease, Weighted Average Remaining Lease Term Additional funding License Agreement, Additional Funding License Agreement, Additional Funding Product sales, net Revenue from Contract with Customer, Excluding Assessed Tax Maximum contingent consideration License Agreement, Contingent Consideration, Maximum License Agreement, Contingent Consideration, Maximum Long-Term Debt, Type [Axis] Long-Term Debt, Type [Axis] Amendment Flag Amendment Flag Reconciliation of income taxes computed using the federal statutory rate to the taxes reported in consolidated statements of operations Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract] Money market funds Money Market Funds [Member] Cash and Cash Equivalents [Axis] Cash and Cash Equivalents [Axis] Intangible assets Deferred Tax Assets, Goodwill and Intangible Assets Tenant improvement allowance Lessee, Operating Lease, Tenant Improvement Allowance Lessee, Operating Lease, Tenant Improvement Allowance Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Restricted stock withheld for employee tax remittance (in shares) Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation Weighted-average discount rate - Operating lease discount rate Operating Lease, Weighted Average Discount Rate, Percent Licensing Agreements Licensing Agreements [Member] Interest paid Interest Paid, Excluding Capitalized Interest, Operating Activities Shares of common stock issued (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period MediWound Ltd MediWound Ltd [Member] MediWound Ltd [Member] Credit Facility [Domain] Credit Facility [Domain] Intangible Assets, net Intangible Assets, Finite-Lived, Policy [Policy Text Block] Basis spread on variable rate (in percent) Debt Instrument, Basis Spread on Variable Rate Useful lives (in years) Property, Plant and Equipment, Useful Life Cost, Product and Service [Extensible List] Cost, Product and Service [Extensible Enumeration] Weighted-average remaining lease term - Finance lease term Finance Lease, Weighted Average Remaining Lease Term Leasehold improvements Leasehold Improvements [Member] Net deferred tax assets and liabilities Deferred Tax Liabilities, Net Measurement of lease liability Payments For Measurement Of Lease Liability Payments For Measurement Of Lease Liability Employee stock purchase plan and service-based stock options Employee Stock And Employee Stock Option [Member] Employee Stock And Employee Stock Option [Member] Diluted (in shares) Diluted weighted-average common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Diluted Grantee Status [Domain] Grantee Status [Domain] Long-term investments Long-term Investments [Member] Long-term Investments [Member] Total Other Commitment Income Tax Authority, Name [Axis] Income Tax Authority, Name [Axis] Right-of-use asset and lease liability recognized Right-of-Use Asset Obtained in Exchange for Finance Lease Liability Secured Overnight Financing Rate (SOFR) Secured Overnight Financing Rate (SOFR) [Member] Secured Overnight Financing Rate (SOFR) Change in estimates related to prior periods Change in Accounting Method Accounted for as Change in Estimate [Member] Expenditures for property and equipment Payments to Acquire Property, Plant, and Equipment Document Annual Report Document Annual Report Expired (in USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Classified as: Balance Sheet Location [Axis] Total assets Assets Research and orphan drug credits Effective Income Tax Rate Reconciliation, Tax Credit, Temporary Differences, Amount Effective Income Tax Rate Reconciliation, Tax Credit, Temporary Differences, Amount Cover [Abstract] Cover [Abstract] Total MACI implants and kits MACI Implants And Kits [Member] MACI Implants And Kits Commercial Paper Commercial Paper, Not Included with Cash and Cash Equivalents [Member] Stock-based compensation expense APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Research and development costs Deferred Tax Assets, Research and Development Costs Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from research and development costs. Amortization of debt issuance costs Amortization of Debt Issuance Costs Contingent consideration License Agreement, Contingent Consideration License Agreement, Contingent Consideration Recurring Fair Value, Recurring [Member] Other long-term liabilities Other Liabilities, Noncurrent Vested (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Short-term investments Short-Term Investments Construction in process Construction in Progress [Member] 2027 Lease Liability Payments Due Year Four Lease Liability Payments Due Year Four Total operating expenses Operating Expenses Consideration payment for license License Agreement, Consideration License Agreement, Consideration Net increase (decrease) in cash, cash equivalents, and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Income Tax Authority, Name [Domain] Income Tax Authority, Name [Domain] 2028 Other Commitment, to be Paid, Year Five Provider or Facility Provider or Facility [Member] Provider or Facility [Member] Time-and-materials contract Time-and-Materials Contract [Member] Equity Component [Domain] Equity Component [Domain] Finance Finance Lease, Liability, Current State State and Local Jurisdiction [Member] Total Contractual Obligation Net operating loss carryforwards Deferred Tax Assets, Operating Loss Carryforwards Debt Instrument [Line Items] Debt Instrument [Line Items] Basic (in shares) Basic weighted-average common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Basic Entity Current Reporting Status Entity Current Reporting Status Concentration Risk Type [Domain] Concentration Risk Type [Domain] Contract rate Fixed-Price Contract [Member] Loss from operations Operating Income (Loss) Customer One Customer One [Member] Customer One Property and equipment, net Deferred Tax Liabilities, Property, Plant and Equipment Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Axis] NexoBrid License and Supply Agreements License Agreement [Text Block] License Agreement [Text Block] Cash and Cash Equivalents Cash and Cash Equivalents [Member] 2025 Contractual Obligation, to be Paid, Year Two Total net deferred tax liabilities Deferred Tax Liabilities, Gross Operating activities: Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Statement Statement [Line Items] Property and Equipment, net Property, Plant and Equipment, Policy [Policy Text Block] Expected to vest (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Outstanding borrowings Long-Term Line of Credit Schedule of fair value of securities, not including cash Debt Securities, Available-for-Sale [Table Text Block] Purchase obligation, automatic renewal, term Purchase Obligation, Automatic Renewal, Term Purchase Obligation, Automatic Renewal, Term Name of Property [Axis] Name of Property [Axis] Contract with Customer, Sales Channel [Domain] Contract with Customer, Sales Channel [Domain] Product [Member]