Document and Entity Information Statement [Table] Statement [Line Items] Statement Balance Sheet Components Entity Registrant Name Entity Central Index Key Document Type Document Period End Date Amendment Flag Current Fiscal Year End Date Entity Current Reporting Status Entity Filer Category Entity Common Stock, Shares Outstanding Document Fiscal Year Focus Document Fiscal Period Focus CONDENSED CONSOLIDATED BALANCE SHEETS Class of Stock [Axis] Class Of Stock [Domain] Class of Stock [Domain] Series B Preferred Stock [Member] Series B voting convertible preferred stock Convertible Preferred Stock [Member] Series B-2 voting convertible preferred stock Assets [Abstract] ASSETS Assets, Current [Abstract] Current assets: Cash Cash at end of period Cash at beginning of period Cash Accounts Receivable, Net, Current Accounts receivable Inventory, Net Inventory Inventory Other Assets, Current Other current assets Assets, Current Total current assets Property, Plant and Equipment, Net Property and equipment, net Total, net Intangible Assets, Net (Excluding Goodwill) Intangible assets Assets Total assets Liabilities and Equity [Abstract] LIABILITIES AND SHAREHOLDERS' EQUITY Liabilities, Current [Abstract] Current liabilities: Accounts Payable and Accrued Liabilities, Current Accounts payable and accrued expenses Total Accrued Employee Benefits, Current Accrued employee benefits Accrued Liabilities Amount accrued for payments of potential milestone payments Verigen payment liability Carrying amount as of the balance sheet date of a liability for an asset retirement obligation of known and estimated obligations associated with exit from or disposal of business activities or restructurings pursuant to a duly authorized plan, which are expected to be paid in the next twelve months or in the normal operating cycle if longer. Costs of such activities include those for one-time termination benefits, termination of an operating lease or other contract, consolidating or closing facilities, relocating employees, and costs associated with an ongoing benefit arrangement, but excludes costs associated with the retirement of a long-lived asset. An asset retirement obligation is a legal obligation associated with the disposal or retirement of a tangible long-lived asset that results from the acquisition, construction or development, or the normal operations of a long-lived asset, except for certain obligations of lessees. Restructuring reserve and asset retirement obligations Restructuring reserve and asset retirement obligation Total Long-term Debt, Current Maturities Current portion of long-term debt Warrants and Rights Outstanding Balance at the end of the period Balance at the beginning of the period Warrant liabilities Liabilities, Current Total current liabilities Long-term Debt, Excluding Current Maturities Long-term debt: Liabilities Total liabilities Commitments and Contingencies. COMMITMENTS AND CONTINGENCIES (Note 14) Stockholders' Equity Attributable to Parent [Abstract] Shareholders' equity: Preferred Stock, Value, Outstanding Total convertible preferred stock Common Stock, Value, Issued Common stock, no par value; shares authorized - 75,000 and 15,000; shares issued and outstanding - 23,786 and 4,723, respectively Accumulated Other Comprehensive Income (Loss), Net of Tax Other comprehensive income Development Stage Enterprise, Deficit Accumulated During Development Stage Accumulated deficit Stockholders' Equity Attributable to Parent Total shareholders' equity Liabilities and Equity Total liabilities and shareholders' equity Preferred Stock, No Par Value Par value of convertible preferred stock (in dollars per share) Preferred Stock, Shares Authorized Convertible preferred stock, shares authorized Convertible Preferred Stock, Shares Reserved for Future Issuance Convertible preferred stock, shares reserved Preferred Stock, Shares Issued Convertible preferred stock, shares issued Preferred Stock, Shares Outstanding Convertible preferred stock, shares outstanding Common Stock, No Par Value Par value of common stock (in dollars per share) Common stock, par value (in dollars per share) Common Stock, Shares Authorized Common Stock, shares authorized Common Stock, Shares, Issued Number of shares of common stock sold Common Stock, shares issued Shares of common stock issued Common Stock, Shares, Outstanding Common Stock, shares outstanding CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS Revenues [Abstract] Revenues: Sales Revenue, Goods, Net Product sales Revenue, Net Total revenues Costs and Expenses [Abstract] Costs and expenses: Cost of Goods Sold Cost of product sales Gross Profit Gross profit Research and Development Expense Research and development Selling, General and Administrative Expense Selling, general and administrative Operating Expenses Total operating expenses Operating Income (Loss) Loss from operations Other Nonoperating Income (Expense) [Abstract] Other income (expense): Fair Value Adjustment of Warrants (Increase) decrease in fair value of warrants Change in fair value of warrants Increase in fair value Business Combination, Bargain Purchase, Gain Recognized, Amount Bargain purchase gain Bargain purchase gain Foreign Currency Transaction Gain (Loss), Realized Foreign currency translation gain Foreign currency translation gain Investment Income, Interest Interest income Interest Expense Interest expense Nonoperating Income (Expense) Total other income (expense) Net Income (Loss) Attributable to Parent Net loss Net loss Net loss Earnings Per Share, Basic and Diluted Net loss per share attributable to common shareholders (Basic and Diluted) (see note 11) (in dollars per share) Net loss per share attributable to common shareholders (basic and diluted) (in dollars per share) Weighted Average Number of Shares Outstanding, Basic and Diluted Weighted average number of common shares outstanding (Basic and Diluted) Weighted-average common shares outstanding CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Other comprehensive income Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent Foreign currency translation Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive loss CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used for operating activities: Depreciation, Depletion and Amortization Depreciation and amortization Share-based Compensation Stock compensation expense Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Increase (Decrease) in Inventories Inventory Increase (Decrease) in Receivables Accounts receivable Increase (Decrease) in Other Current Assets Other current assets Increase (Decrease) in Accounts Payable and Accrued Liabilities Accounts payable and accrued expenses Increase (Decrease) in Employee Related Liabilities Accrued employee benefits Increase (Decrease) in Accrued Liabilities Verigen payment liability The increase (decrease) during the reporting period in the carrying amount of restructuring reserve and asset retirement obligations. Increase Decrease in Restructuring Reserve and Asset Retirement Obligations Restructuring reserve and asset retirement obligation Net Cash Provided by (Used in) Operating Activities, Continuing Operations Net cash used for operating activities Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Investing activities: Payments to Acquire Businesses, Net of Cash Acquired Acquisition of CTRM business, net of cash acquired Payments to Acquire Property, Plant, and Equipment Property and equipment purchases Net Cash Provided by (Used in) Investing Activities, Continuing Operations Net cash used for investing activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Financing activities: Proceeds from Issuance of Preferred Stock and Preference Stock Net proceeds from issuance of common stock and warrants Repayments of Debt Pay downs of debt Net Cash Provided by (Used in) Financing Activities, Continuing Operations Net cash provided by financing activities Effect of Exchange Rate on Cash and Cash Equivalents Effect of exchange rate changes on cash Net Cash Provided by (Used in) Continuing Operations Net increase (decrease) in cash Supplemental Cash Flow Information [Abstract] Supplemental cash flow information (non-cash): Preferred Stock, Accretion of Redemption Discount Accretion of convertible preferred stock Business Combination, Consideration Transferred, Liabilities Incurred Promissory note Acquisition of business through issuance of promissory note Stock and Warrants Issued During Period, Value, Preferred Stock and Warrants Warrants exchanged for common stock Capital Lease Obligations Incurred Equipment acquired under capital lease obligations ORGANIZATION: Nature of Operations [Text Block] ORGANIZATION: BASIS OF PRESENTATION: Basis of Accounting [Text Block] BASIS OF PRESENTATION: SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES AND NEWLY ISSUED ACCOUNTING STANDARDS: Significant Accounting Policies [Text Block] SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES AND NEWLY ISSUED ACCOUNTING STANDARDS: ACQUISITIONS Business Combination Disclosure [Text Block] ACQUISITIONS RESTRUCTURING: Restructuring and Related Activities Disclosure [Text Block] RESTRUCTURING: STOCK-BASED COMPENSATION Disclosure of Compensation Related Costs, Share-based Payments [Text Block] STOCK-BASED COMPENSATION BALANCE SHEET COMPONENTS: Supplemental Balance Sheet Disclosures [Text Block] BALANCE SHEET COMPONENTS: FAIR VALUE MEASUREMENTS: Fair Value Disclosures [Text Block] FAIR VALUE MEASUREMENTS: STOCK PURCHASE WARRANTS: The entire disclosure for warrants including description, amounts outstanding, fair value calculation and estimates. Warrants and Rights Note Disclosure [Text Block] STOCK PURCHASE WARRANTS: SERIES B CONVERTIBLE PREFERRED STOCK: Preferred Stock [Text Block] SERIES B CONVERTIBLE PREFERRED STOCK: Net Loss Per Common Share: Net loss per share Earnings Per Share [Text Block] Net Loss Per Common Share: SHAREHOLDERS' EQUITY: Stockholders' Equity Note Disclosure [Text Block] SHAREHOLDERS' EQUITY: CONCENTRATION OF CREDIT RISK Concentration Risk Disclosure [Text Block] CONCENTRATION OF CREDIT RISK COMMITMENTS AND CONTINGENCIES Commitments and Contingencies Disclosure [Text Block] COMMITMENTS AND CONTINGENCIES LIQUIDITY: Liquidation Basis of Accounting [Text Block] LIQUIDITY: Inventory, Policy [Policy Text Block] Inventory Receivables, Policy [Policy Text Block] Accounts Receivable Property, Plant and Equipment, Policy [Policy Text Block] Property, Plant and Equipment Intangible Assets, Finite-Lived, Policy [Policy Text Block] Intangible Assets Impairment or Disposal of Long-Lived Assets, Including Intangible Assets, Policy [Policy Text Block] Impairment of Intangible Assets and Other Long-Lived assets Foreign Currency Transactions and Translations Policy [Policy Text Block] Foreign Currency Translation Revenue Recognition, Policy [Policy Text Block] Revenue Recognition Research and Development Expense, Policy [Policy Text Block] Research and Development Expense New Accounting Pronouncements, Policy [Policy Text Block] Newly issued Accounting Standards Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block] Schedule of total purchase price allocation Tabular disclosure of the consideration transferred, consisting of acquisition-date fair value of assets transferred by the acquirer, liabilities incurred by the acquirer, and equity interest issued by the acquirer. Schedule of Business Combination Consideration Transferred [Table Text Block] Schedule of preliminary purchase price allocation Finite-Lived and Indefinite-Lived Intangible Assets Acquired as Part of Business Combination [Table Text Block] Summary of identifiable intangible assets acquired and their estimated useful lives Business Acquisition, Pro Forma Information [Table Text Block] Schedule of unaudited pro forma condensed combined statements Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule of weighted average assumptions used to estimate fair value of each service-based stock option grant Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] Summary of activity for service-based stock options Schedule of Inventory, Current [Table Text Block] Schedule of inventory Property, Plant and Equipment [Table Text Block] Schedule of property and equipment, net Schedule of Finite-Lived Intangible Assets [Table Text Block] Schedule of intangible assets, net Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block] Schedule of estimated future amortization expense Schedule of Accounts Payable and Accrued Liabilities [Table Text Block] Schedule of accounts payable and accrued expenses Tabular disclosure of entity's restructuring reserve that occurred during the period associated with the exit from or disposal of business activities or restructurings for each major type of cost and carrying amount of a liability for asset retirement obligations. Schedule of Restructuring Reserve by Type of Cost and Asset Retirement Obligations Schedule of Restructuring Reserve and asset retirement obligation Fair Value, Liabilities Measured on Recurring Basis [Table Text Block] Summary of valuation of the Company's investments and financial instruments that are measured at fair value on a recurring basis Tabular disclosure of change in the estimated fair value of the warrant liabilities. Schedule of Change in Estimated Fair Value of Warrant Liabilities [Table Text Block] Summary of change in estimated fair value of warrant liabilities Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block] Schedule of reconciliation of beginning and ending balances for the Company's fair value measurements using Level 3 inputs Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] Schedule of warrants outstanding Tabular disclosure of the significant assumptions used during the period to estimate the fair value of warrant liabilities, including, but not limited to: (a) expected term of instruments, (b) expected volatility of the entity's shares, (c) closing stock price, (d) risk-free rate, and (e) dividend rate. Schedule of Class of Warrant or Right Valuation Assumptions [Table Text Block] Schedule of assumptions used in calculating estimated fair value of warrants Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Schedule of net loss attributable to common shareholders and share data used in the basic and diluted earnings per share computations using the two class method Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block] Schedule of future minimum payments related to leases Disclosure pertaining to organization, consolidation and presentation of financial statements. Organization Consolidation and Presentation of Financial Statements [Table] Business Acquisition [Axis] Business Acquisition Acquiree [Domain] Business Acquisition, Acquiree [Domain] Represents information pertaining to cell therapy and regenerative medicine business. Cell Therapy And Regenerative Medicine Business [Member] CTRM Business Organization Consolidation and Presentation of Financial Statements [Line Items] Organization Represents the number of patents and patent applications acquired by the entity. Number of Patents and Patent Applications Acquired Number of patents and patents applications acquired Number of Reportable Segments Number of reportable segments Property, Plant and Equipment [Table] Property, Plant and Equipment, Type [Axis] Property Plant And Equipment Type [Domain] Property, Plant and Equipment, Type [Domain] Represents information pertaining to equipment and computers. Equipment And Computers [Member] Equipment and computers Furniture And Fixtures [Member] Furniture and fixtures Represents information pertaining to building improvements and leasehold improvements. Building Improvements And Leasehold Improvements [Member] Building improvements and leasehold improvements Range [Axis] Range [Member] Range [Domain] Minimum [Member] Minimum Maximum [Member] Maximum Property, Plant and Equipment [Line Items] Property, Plant and Equipment Property and equipment, net: Property, Plant and Equipment, Useful Life Useful lives Schedule of Business Acquisitions, by Acquisition [Table] Finite-Lived Intangible Assets by Major Class [Axis] Finite Lived Intangible Assets Major Class Name [Domain] Finite-Lived Intangible Assets, Major Class Name [Domain] Contractual Rights [Member] Commercial rights Legal Entity [Axis] Entity [Domain] Entity [Domain] Represents information pertaining to Sanofi. Sanofi [Member] Sanofi Represents information pertaining to Genzyme Biosurgery ApS. Genzyme Biosurgery Aps [Member] Genzyme Biosurgery ApS Business Acquisition [Line Items] Acquisitions