0001001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 1001002 - Statement - CONSOLIDATED BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 1002003 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 1003004 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS link:presentationLink link:calculationLink link:definitionLink 1004005 - Statement - CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS) link:presentationLink link:calculationLink link:definitionLink 1005006 - Statement - CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY link:presentationLink link:calculationLink link:definitionLink 1006007 - Statement - CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 1007008 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 2101101 - Disclosure - Organization link:presentationLink link:calculationLink link:definitionLink 2402401 - Disclosure - Organization (Details) link:presentationLink link:calculationLink link:definitionLink 2103102 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 2204201 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 2305301 - Disclosure - Summary of Significant Accounting Policies (Tables) link:presentationLink link:calculationLink link:definitionLink 2406402 - Disclosure - Summary of Significant Accounting Policies - Supplementary cash flows information (Details) link:presentationLink link:calculationLink link:definitionLink 2407403 - Disclosure - Summary of Significant Accounting Policies - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 2108103 - Disclosure - Recent Accounting Pronouncements link:presentationLink link:calculationLink link:definitionLink 2109104 - Disclosure - Revenue link:presentationLink link:calculationLink link:definitionLink 2310302 - Disclosure - Revenue (Tables) link:presentationLink link:calculationLink link:definitionLink 2411404 - Disclosure - Revenue - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 2412405 - Disclosure - Revenue - Disaggregation of Revenue (Details) link:presentationLink link:calculationLink link:definitionLink 2413406 - Disclosure - Revenue - Schedules of concentration of risk (Details) link:presentationLink link:calculationLink link:definitionLink 2114105 - Disclosure - Selected Balance Sheet Components link:presentationLink link:calculationLink link:definitionLink 2315303 - Disclosure - Selected Balance Sheet Components (Tables) link:presentationLink link:calculationLink link:definitionLink 2416407 - Disclosure - Selected Balance Sheet Components - Schedule of inventory (Details) link:presentationLink link:calculationLink link:definitionLink 2417408 - Disclosure - Selected Balance Sheet Components - Schedule of property and equipment, net (Details) link:presentationLink link:calculationLink link:definitionLink 2418409 - Disclosure - Selected Balance Sheet Components - Schedule of accrued expenses (Details) link:presentationLink link:calculationLink link:definitionLink 2119106 - Disclosure - Debt link:presentationLink link:calculationLink link:definitionLink 2420410 - Disclosure - Debt (Details) link:presentationLink link:calculationLink link:definitionLink 2121107 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 2322304 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 2423411 - Disclosure - Leases - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 2424412 - Disclosure - Leases - Assets And Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 2425413 - Disclosure - Leases - Maturities of lease liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 2425413 - Disclosure - Leases - Maturities of lease liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 2425413 - Disclosure - Leases - Maturities of lease liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 2426414 - Disclosure - Leases - Lease term and discount rate (Details) link:presentationLink link:calculationLink link:definitionLink 2127108 - Disclosure - Cash Equivalents and Investments link:presentationLink link:calculationLink link:definitionLink 2328305 - Disclosure - Cash Equivalents and Investments (Tables) link:presentationLink link:calculationLink link:definitionLink 2429415 - Disclosure - Cash Equivalents and Investments (Details) link:presentationLink link:calculationLink link:definitionLink 2130109 - Disclosure - Stock-Based Compensation link:presentationLink link:calculationLink link:definitionLink 2331306 - Disclosure - Stock-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 2432416 - Disclosure - Stock-Based Compensation - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 2433417 - Disclosure - Stock-Based Compensation - Schedule of fair value assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 2434418 - Disclosure - Stock-Based Compensation - Schedule of activity for service-based stock options (Details) link:presentationLink link:calculationLink link:definitionLink 2435419 - Disclosure - Stock-Based Compensation - Schedule of restricted stock awards activity (Details) link:presentationLink link:calculationLink link:definitionLink 2436420 - Disclosure - Stock-Based Compensation - Schedule of non-cash stock-based compensation expense (Details) link:presentationLink link:calculationLink link:definitionLink 2137110 - Disclosure - Net Income (Loss) Per Common Share link:presentationLink link:calculationLink link:definitionLink 2338307 - Disclosure - Net Income (Loss) Per Common Share (Tables) link:presentationLink link:calculationLink link:definitionLink 2439421 - Disclosure - Net Income (Loss) Per Common Share (Details) link:presentationLink link:calculationLink link:definitionLink 2140111 - Disclosure - Shareholders' Equity link:presentationLink link:calculationLink link:definitionLink 2441422 - Disclosure - Shareholders' Equity - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 2142112 - Disclosure - Stock Purchase Warrants link:presentationLink link:calculationLink link:definitionLink 2443423 - Disclosure - Stock Purchase Warrants (Details) link:presentationLink link:calculationLink link:definitionLink 2144113 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 2345308 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 2446424 - Disclosure - Fair Value Measurements (Details) link:presentationLink link:calculationLink link:definitionLink 2147114 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 2348309 - Disclosure - Income Taxes (Tables) link:presentationLink link:calculationLink link:definitionLink 2449425 - Disclosure - Income Taxes - Components of Income (Loss) Before Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 2450426 - Disclosure - Income Taxes - Deferred Tax Assets (Details) link:presentationLink link:calculationLink link:definitionLink 2451427 - Disclosure - Income Taxes - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 2152115 - Disclosure - Employee Savings Plan link:presentationLink link:calculationLink link:definitionLink 2453428 - Disclosure - Employee Savings Plan (Details) link:presentationLink link:calculationLink link:definitionLink 2154116 - Disclosure - Nexobrid License and Supply Agreements link:presentationLink link:calculationLink link:definitionLink 2455429 - Disclosure - NexoBrid License and Supply Agreements (Details) link:presentationLink link:calculationLink link:definitionLink 2156117 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 2357310 - Disclosure - Commitments and Contingencies (Tables) link:presentationLink link:calculationLink link:definitionLink 2458430 - Disclosure - Commitments and Contingencies - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 2459431 - Disclosure - Commitments and Contingencies - Future Minimum Payments (Details) link:presentationLink link:calculationLink link:definitionLink 2160118 - Disclosure - Supplementary Quarterly Financial Information (unaudited) link:presentationLink link:calculationLink link:definitionLink 2361311 - Disclosure - Supplementary Quarterly Financial Information (unaudited) (Tables) link:presentationLink link:calculationLink link:definitionLink 2462432 - Disclosure - Supplementary Quarterly Financial Information (unaudited) (Details) link:presentationLink link:calculationLink link:definitionLink