SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G
                                 (Rule 13d-102)

  INFORMATION   TO  BE  INCLUDED  IN  STATEMENTS   FILED  PURSUANT  TO  RULES
  13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b)

                               (Amendment No. 1)*

                             Aastrom Biosciences, Inc.
                        ---------------------------------
                                (Name of Issuer)

                           Common Stock, no par value
--------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                   00253U107
                               -------------------
                                 (CUSIP Number)

                                December 31, 2004
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             (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

       [ ]        Rule 13d-1(b)
       [X]        Rule 13d-1(c)
       [ ]        Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

                                  SCHEDULE 13G
CUSIP NO. 00253U107                                               Page 2 of 7

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1    NAMES OF REPORTING PERSONS
     I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (Entities Only)

     Cranshire Capital, L.P.
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2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP     (a) [ ]
                                                          (b) [ ]
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3    SEC USE ONLY

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4    CITIZENSHIP OR PLACE OF ORGANIZATION

     Illinois
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NUMBER OF      5    SOLE VOTING POWER

SHARES              N/A
               --------------------------------------------------------------
BENEFICIALLY   6    SHARED VOTING POWER

OWNED BY            N/A
               --------------------------------------------------------------
EACH           7    SOLE DISPOSITIVE POWER

REPORTING           N/A
               --------------------------------------------------------------
PERSON         8    SHARED DISPOSITIVE POWER

WITH                N/A
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9    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     N/A
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10   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

                                                                   [ ]
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11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     Less than 5%
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12   TYPE OF REPORTING PERSON

     PN
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SCHEDULE 13G CUSIP NO. 00253U107 Page 3 of 7 ----------------------------------------------------------------------------- 1 NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (Entities Only) Downsview Capital, Inc. ----------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) [ ] (b) [ ] ----------------------------------------------------------------------------- 3 SEC USE ONLY ----------------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION Illinois ----------------------------------------------------------------------------- NUMBER OF 5 SOLE VOTING POWER SHARES N/A -------------------------------------------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY N/A -------------------------------------------------------------- EACH 7 SOLE DISPOSITIVE POWER REPORTING N/A -------------------------------------------------------------- PERSON 8 SHARED DISPOSITIVE POWER WITH N/A ----------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON N/A ----------------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES [ ] ----------------------------------------------------------------------------- 11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) Less than 5% ----------------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON CO -----------------------------------------------------------------------------

SCHEDULE 13G CUSIP NO. 00253U107 Page 4 of 7 ----------------------------------------------------------------------------- 1 NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (Entities Only) Mitchell P. Kopin ----------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) [ ] (b) [ ] ----------------------------------------------------------------------------- 3 SEC USE ONLY ----------------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION U.S.A. ----------------------------------------------------------------------------- NUMBER OF 5 SOLE VOTING POWER SHARES N/A -------------------------------------------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY N/A -------------------------------------------------------------- EACH 7 SOLE DISPOSITIVE POWER REPORTING N/A -------------------------------------------------------------- PERSON 8 SHARED DISPOSITIVE POWER WITH N/A ----------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON N/A ----------------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES [ ] ----------------------------------------------------------------------------- 11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) Less than 5% ----------------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON IN -----------------------------------------------------------------------------

SCHEDULE 13G CUSIP NO. 00253U107 5 of 7 Item 1(a). Name of Issuer: Aastrom Biosciences, Inc., a Michigan corporation (the "Issuer") Item 1(b). Address of Issuer's Principal Executive Offices: 24 Frank Lloyd Wright Dr. PO Box 376 Ann Arbor, Michigan 48106 Items 2(a), Name of Persons Filing, Address of Principal Business (b) and (c). Office and Citizenship: This Amendment No. 1 to Schedule 13G is being filed on behalf of (i) Cranshire Capital, L.P., an Illinois limited partnership ("Cranshire"), (ii) Downsview Capital, Inc., an Illinois corporation ("Downsview") and (iii) Mitchell P. Kopin, an individual who is a citizen of the U.S.A. ("Kopin," together with Cranshire and Downsview, the "Reporting Persons"). The Reporting Persons have entered into a Joint Filing Agreement, a copy of which is filed with this Amendment No. 1 to Schedule 13G as Exhibit 1, pursuant to which the Reporting Persons have agreed to file this Schedule 13G jointly in accordance with the provisions of Rule 13d-1(k) of the Securities Exchange Act of 1934, as amended. The principal business office of each of the Reporting Persons is 666 Dundee Road, Suite 1901, Northbrook, Illinois, 60062. Item 2(d). Title of Class of Securities: Common Stock, no par value, of the Issuer (the "Common Stock") Item 2(e). CUSIP Number: 00253U107 Item 3. Not applicable. Item 4. Ownership. (a) Amount beneficially owned: N/A (b) Percent of class: Less than 5% SCHEDULE 13G CUSIP NO. 00253U107 Page 6 of 7 (c) Number of shares to which such persons has: ------------------------------------------ (i) Sole power to vote or direct the vote: N/A (ii) Shared power to vote or direct the vote: N/A (iii)Sole power to dispose or to direct the disposition of: N/A (iv) Shared power to dispose of or direct the disposition of: N/A Item 5. Ownership of Five Percent or Less of a Class. If this statement is being filed to report the fact that as of the date hereof the reporting persons have ceased to be the beneficial owner of more than five percent of the class of securities, check the following [X]. Item 6. Ownership of More than Five Percent on Behalf of Another Person. N/A Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported By the Parent Holding Company. N/A Item 8. Identification and Classification of Members of the Group. N/A Item 9. Notice of Dissolution of a Group. N/A Item 10. Certification. By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

SCHEDULE 13G CUSIP NO. 00253U107 Page 7 of 7 SIGNATURE After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. Dated: February 4, 2005 CRANSHIRE CAPITAL, L.P. By: Downsview Capital, Inc., its general partner By:/s/ Mitchell P. Kopin ------------------------------ Mitchell P. Kopin, President DOWNSVIEW CAPITAL, INC. By:/s/ Mitchell P. Kopin ------------------------------ Mitchell P. Kopin, President /s/ Mitchell P. Kopin --------------------------------- Mitchell P. Kopin

SCHEDULE 13G CUSIP NO. 00253U107 Exhibit 1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the undersigned agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to certain shares of Common Stock, no par value of Aastrom Biosciences, Inc., and further agree that this Joint Filing Agreement shall be included as an exhibit to such joint filings. The undersigned further agree that each party hereto is responsible for the timely filing of such Schedule 13G and any amendments thereto, and for the completeness and accuracy of the information concerning such party contained therein; provided, however, that no party is responsible for the completeness or accuracy of the information concerning any other party making the filing, unless such party knows or has reason to believe that such information is inaccurate. IN WITNESS WHEREOF, the parties have executed this Joint Filing Agreement on February 4, 2005. CRANSHIRE CAPITAL, L.P. By: Downsview Capital, Inc., its general partner By:/s/ Mitchell P. Kopin ------------------------------- Mitchell P. Kopin, President DOWNSVIEW CAPITAL, INC. By:/s/ Mitchell P. Kopin ------------------------------- Mitchell P. Kopin, President /s/ Mitchell P. Kopin ---------------------------------- Mitchell P. Kopin