1  NAME OF REPORTING PERSON - State Treasurer, State of Michigan 
   IRS IDENTIFICATION - 38-2836023 
2  CHECK IF MEMBER OF A GROUP - Not applicable 
3  SEC use only 
4  CITIZENSHIP - State of Michigan 
5  SOLE VOTING POWER - 1,338,724 (these shares included in item 7 below)
6  SHARED VOTING POWER - None 
7  SOLE DISPOSITIVE POWER - 1,338,724 
8  SHARED DISPOSITIVE POWER - None 
9  AGGREGATE AMOUNT OWNED - 1,338,724 
10 IF AGGREGATE AMOUNT EXCLUDES CERTAIN SHARES - Not applicable 
11 PERCENT OF CLASS REPRESENTED - 10.1% 
12 TYPE OF REPORTING PERSON - see pages below 
 
 

1a NAME OF ISSUER - Aastrom Biosciences, Inc.
1b ADDRESS OF ISSUER - 24 Frank Lloyd Wright Drive
                       P.O. Box 376
                       Ann Arbor, MI  48106
2a NAME OF FILER - State Treasurer, State of Michigan
2b ADDRESS OF FILER - Michigan Department of Treasury
                      Alternative Investments Division
                      P.O. Box 15128
                      Lansing, MI  48909
2c CITIZENSHIP - State of Michigan
2d CLASS OF SECURITIES - Common Stock
2e CUSIP NUMBER - 00253U107
3  PERSON FILING - Not applicable
4  OWNERSHIP - Reference Item 5 through 11 on previous page
5  OWNERSHIP UNDER 5% - Not applicable
6  OWNERSHIP OVER 5% - Not applicable
7  INDENTIFICATION OF SUBSIDIARY - Not applicable
8  IDENTIFICATION OF MEMBERS - Not applicable
9  NOTICE OF DISSOLUTION - Not applicable
10 CERTIFICATION - Not applicable

Pursuant to State Law (Section 91 of Act No. 380 of the Public Acts of 1965,
as amended), the State Treasurer, State of Michigan is the investment
fiduciary for the following four State sponsored retirement systems:
Public School Employees' Retirement System; State Employees' Retirement System;
Michigan State Police Retirement System; and Judges' Retirement System.

The Michigan Department of Treasury's Bureau of Investments performs the
investment function, under the direction and on behalf of the State Treasurer.

The aforementioned State Law created an Investment Advisory Committee comprised
of the Director of the Department of Commerce, the Director of the Department
of Management & Budget, or their duly authorized representatives,
and three public members appointed by the Governor with the advice and consent
of the Senate.  The committee meets quarterly and reviews investments, goals,
and objectives, and may submit recommendations to the State Treasurer.
The Investment Advisory Committee may also, by a majority vote, direct the
State Treasurer to dispose of any holdings which in the committee's judgement
is not suitable for the funds involved, and may by unanimous vote direct the
State Treasurer to make specific investments.

Act No. 314 of the Public Acts of 1965, as amended, authorizes the investment
of assets of public employee retirement systems or plans created and
established by the state or any political subdivision.

The acquisition of equity securities are made for investment purposes only.
Investments in equity securities are made from the assets of the
aforementioned four retirement systems with total assets of approximately
$40.0 billion.  The retirement systems derive revenue from employer and
employee contributions, court fees, and investment income.






Name:  Mr. Douglas B. Roberts

Business Address: Michigan Department of Treasury
                  P.O. Box 15128
                  Lansing, Michigan  48901

Principal Occupation:  State Treasurer, State of Michigan

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America





Name:  Mr. Samuel Valenti, III

Business Address: Masco Corporation
                  21001 Van Born Road
                  Taylor, Michigan  48180

Principal Occupation:  Vice President of Investments

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America






Name:  Dr. Paul W. McCracken

Business Address: University of Michigan
                  School of Business Administration
                  701 Tappan
                  Ann Arbor, MI  48109-1234

Principal Occupation:  Consultant

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America






Name:  Mr. Farris W. Womack

Business Address: University of Michigan
                  Fleming Admin. Bldg., Room 3014
                  503 Thompson Street
                  Ann Arbor, MI  48109-1340

Principal Occupation:  Executive Vice President and Chief Financial Officer

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America






Name:  Ms. Kathleen M. Wilbur

Business Address: Department of Commerce
                  Director's Office
                  4th Floor, Law Building
                  Box 30004
                  Lansing, Michigan  48909

Principal Occupation:  Director, Michigan Department of Commerce

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America





Name:  Roy A. Pentilla

Business Address: Michigan Department of Treasury
                  P.O. Box 15128
                  Lansing, Michigan  48901

Principal Occupation:  Deputy Director, Bureau of Investments

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America






Name:  Alan H. Van Noord

Business Address: Michigan Department of Treasury
                  P.O. Box 15128
                  Lansing, Michigan  48901

Principal Occupation:  Administrator, Stock Analysis Division

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America






Name:  Paul R. Nelson, II

Business Address: Michigan Department of Treasury
                  P.O. Box 15128
                  Lansing, Michigan  48901

Principal Occupation:  Administrator, Fixed Income Analysis Division

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America






Name:  Linda J. Rose

Business Address: Michigan Department of Treasury
                  P.O. Box 15128
                  Lansing, Michigan  48901

Principal Occupation:  Acting Administrator, Alternative Investments Division

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America






Name:  Milan J. Maat

Business Address: Michigan Department of Treasury
                  P.O. Box 15128
                  Lansing, Michigan  48901

Principal Occupation:  Administrator, Short Term Investment Division

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America






Name:  Vernon L. Johnson

Business Address: Michigan Department of Treasury
                  P.O. Box 15128
                  Lansing, Michigan  48901

Principal Occupation:  Administrator, Trust Accounting Division

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America






Name:  Philip L. Van Syckle

Business Address: Michigan Department of Treasury
                  P.O. Box 15128
                  Lansing, Michigan  48901

Principal Occupation:  Administrator, Mortgage and Real Estate Division

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America






Name:  Richard J. Holcomb

Business Address: Michigan Department of Treasury
                  P.O. Box 15128
                  Lansing, Michigan  48901

Principal Occupation:  Administrator, Quantitative Analysis Division

Criminal convictions during the last five years:  None

Civil finding or violation, or injunction against violation, of federal or
state securities laws during the last five years:  None

Citizenship:  United States of America

After resonable inquiry and to the best of my knowledge and belief,

I certify that the information set forth in this statement,

is true, complete and correct.



Date:  01-30-98

Signed:  Roy A. Pentilla, Acting Director, Bureau of Investments