UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. )* -------- Aastrom Biosciences, Inc. ----------------------------------------------------------------- (Name of Issuer) Common Stock, No Par Value ----------------------------------------------------------------- (Title of Class of Securities) 00253U107 ---------------------------- (CUSIP Number) August 1, 1997 ----------------------------------------------------------------- (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [ ] Rule 13d-1(b) [x] Rule 13d-1(c) [ ] Rule 13d-1(d) *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). Page 1 of 4 pagesCUSIP NO. 00253U107 --------- ______________________________________________________________________________ 1. NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY). Pfizer Inc. 13-5315170 ______________________________________________________________________________ 2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) (a)_____ (b)_____ ______________________________________________________________________________ 3. SEC USE ONLY ______________________________________________________________________________ 4. CITIZENSHIP OR PLACE OF ORGANIZATION Delaware ______________________________________________________________________________ 5. SOLE VOTING POWER NUMBER OF 864,546 SHARES _______________________________________________________________ BENEFICIALLY 6. SHARED VOTING POWER OWNED BY 0 EACH REPORTING _______________________________________________________________ PERSON 7. SOLE DISPOSITIVE POWER WITH: 864,546 _______________________________________________________________ 8. SHARED DISPOSITIVE POWER 0 ______________________________________________________________________________ 9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 864,546 ______________________________________________________________________________ 10. CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)____ ______________________________________________________________________________ 11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 6.4% ______________________________________________________________________________ 12. TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) CO ______________________________________________________________________________ Page 2 of 4 pages ITEM 1. (a) Name of Issuer: Aastrom Biosciences, Inc. (b) Address of Issuer's Principal Executive Offices: 24 Frank Lloyd Wright Drive P. O. Box 376 Ann Arbor, MI 48106 ITEM 2. (a) Name of Person Filing: Pfizer Inc. (b) Address of Principal Business Office or, if none, Residence: 235 East 42nd Street New York, NY 10017 (c) Citizenship: Delaware (d) Title of Class of Securities: Common Stock, No Par Value (e) CUSIP Number: 00253U107 ITEM 3. IF THIS STATEMENT IS FILED PURSUANT TO RULE 13d-1(b) OR RULE 13d-2(b) OR (c), CHECK WHETHER THE PERSON FILING IS A: Not applicable ITEM 4. OWNERSHIP (a) Amount beneficially owned: 864,546 (b) Percent of class: 6.4% (c) Number of shares as to which the person has: (i) Sole power to vote or to direct the vote: 864,546 (ii) Shared power to vote or to direct the vote: 0 (iii) Sole power to dispose or to direct the disposition of: 864,546 (iv) Shared power to dispose or to direct the disposition of: 0 Page 3 of 4 pages ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS Not applicable ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON Not applicable ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY Not applicable ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP Not applicable ITEM 9. NOTICE OF DISSOLUTION OF GROUP Not applicable ITEM 10. CERTIFICATION By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect. SIGNATURE After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. Date: May 28, 1998 PFIZER INC. By /s/ MARGARET M. FORAN ---------------------------- Name: Margaret M. Foran Title: Assistant Secretary Page 4 of 4 pages