Ann Arbor, MI, November 1, 2005 -- Aastrom Biosciences (NASDAQ: ASTM) announces the following Webcast:

What: Aastrom Biosciences Fiscal Year End 2005 Annual Meeting of Shareholders

When: Wednesday, November 2, 2005 @ 8:30 AM Eastern

Where: Link to Aastrom FY2005 Annual Meeting of Shareholders

How: For live over the Internet access, simply log on to the web at the link above. Shareholders and other interested parties will be able to listen to the entire Annual Meeting of Shareholders, and view the slides during the presentation after the business portion of the meeting. Only shareholders in attendance at the meeting will be able to participate in the Question & Answer session.

Contact: Kris Maly, Investor Relations Department, (734) 930-5777 or mail@aastrom.com

If you are unable to listen to the live webcast, the meeting will be archived at http://www.investorcalendar.com/ for 30 days.

Aastrom Biosciences, Inc. (Nasdaq: ASTM) is developing patient-specific products for the repair or regeneration of human tissues, utilizing the Company's proprietary adult stem cell technology. Aastrom's strategic position in the tissue regeneration sector is enabled by its proprietary Tissue Repair Cells (TRCs), a mix of bone marrow-derived adult stem and progenitor cells manufactured in the AastromReplicell® System, an industry-unique automated cell production system. TRCs are the core component of the products Aastrom is developing for severe bone fractures, ischemic vascular disease, jaw reconstruction and spine fusion, with Phase I/II level clinical trials active in the U.S. and EU for some of these indications.

For more information, visit Aastrom's website at www.aastrom.com.